Evidence map›Paper›PMID 31551805›Full record

ArticleFrontiers in physiology2019

Exercise and Arterial Stiffness in the Elderly: A Combined Cross-Sectional and Randomized Controlled Trial (EXAMIN AGE).

Arne Deiseroth, Lukas Streese, Sabrina Köchli, Romy Sandra Wüst, Denis Infanger, Arno Schmidt-Trucksäss, Henner Hanssen

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02796976 (Exercise, Arterial Cross-Talk Modulation and Inflammation in an Ageing Population), which is not on this map. Cited by 31 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02796976 nacompletednot on this map

Exercise, Arterial Cross-Talk Modulation and Inflammation in an Ageing Population (ExAMIN AGE)

TypeinterventionalSponsorUniversity of BaselRan2016 to 2018Enrolled158ConditionsCardiovascular Disease, Obesity, Atherosclerosis, HeartArmsTraining or control condition
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  14. Physical Activity and Arterial Stiffness: A Narrative Review.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arne DeiserothDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Lukas StreeseDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Sabrina KöchliDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Romy Sandra WüstDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Denis InfangerDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Arno Schmidt-TrucksässDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.
Henner HanssenDepartment of Sport, Exercise and Health, Medical Faculty, University of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArterial stiffness (AST) is a main determinant of cardiovascular (CV) mortality. Long-term physical activity (PA) is considered to decrease age-related progression of AST but effects of short-term exercise interventions on AST remain unclear.

methodsIn a combined cross-sectional and interventional study approach, we investigated the effects of long-term PA and short-term high-intensity interval training (HIIT) on AST in an older population. 147 older individuals (mean age 59 ± 7 years) were assigned to three groups according to their PA and CV risk profile and compared: healthy active (HA,

resultsHigher CRF was associated with lower PWV ( DISCUSSION: SR show higher PWV compared to HS and long-term PA is associated with lower PWV. Reduction of AST following short-term HIIT seems to depend on a concomitant decrease in blood pressure. Our study puts into perspective the effects of long- and short-term exercise on arterial wall integrity as treatment options for CV prevention in an older population. CLINICAL

trial registrationClinicalTrials.gov: NCT02796976 (https://clinicaltrials.gov/ct2/show/NCT02796976).

Indexed as

agingcardiovascular riskhigh-intensity interval trainingphysical activitypulse wave velocity

Identifiers

PMID31551805
PMCPMC6738015

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.