ArticleFrontiers in pharmacology2019
Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells.
Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
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- Arecoline regulates glycolipid and endoplasmic reticulum metabolisms in adult grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Mitochondria-Associated Membranes as Key Regulators in Cellular Homeostasis and the Potential Impact of Exercise on Insulin Resistance.International journal of molecular sciences · 2024Review
- Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024.Frontiers in nutrition · 2024Article
- Lipidomic and transcriptomic profiles provide new insights into the triacylglycerol and glucose handling capacities of the Arctic fox.Frontiers in veterinary science · 2024Article
- Glucose Uptake Is Increased by Estradiol Dipropionate in L6 Skeletal Muscle Cells.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Andrographolide Promotes Uptake of Glucose and GLUT4 Transport through the PKC Pathway in L6 Cells.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium Signalling Pathway.International journal of molecular sciences · 2022Article
- Stevioside Attenuates Insulin Resistance in Skeletal Muscle by Facilitating IR/IRS-1/Akt/GLUT 4 Signaling Pathways: An In Vivo and In Silico Approach.Molecules (Basel, Switzerland) · 2021Article
- Identification of CMolecules (Basel, Switzerland) · 2021Article
- Plants Secondary Metabolites as Blood Glucose-Lowering Molecules.Molecules (Basel, Switzerland) · 2021Review
- Davidones F and G, Two Novel Flavonoids fromMolecules (Basel, Switzerland) · 2021Article
- Vitamin D Levels and the Risk of Posttransplant Diabetes Mellitus After Kidney Transplantation.Progress in transplantation (Aliso Viejo, Calif.) · 2021Article
- Chemical Constituents from Roots ofMolecules (Basel, Switzerland) · 2021Article
- Anti-Obesity and Antidiabetic Effects of Nelumbinis Semen Powder in High-Fat Diet-Induced Obese C57BL/6 Mice.Nutrients · 2020Article
- The Molecular Mechanisms Underlying Mitochondria-Associated Endoplasmic Reticulum Membrane-Induced Insulin Resistance.Frontiers in endocrinology · 2020Review
- Red riceFood & nutrition research · 2020Article
- Cassia Abbreviata Enhances Glucose Uptake and Glucose Transporter 4 Translocation in C2C12 Mouse Skeletal Muscle Cells.Journal of evidence-based integrative medicineArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucose transporter 4 (GLUT4) is involved in regulating glucose uptake in striated muscle, liver, and adipose tissue. Neferine is a dibenzyl isoquinoline alkaloid derived from dietary lotus seeds and has multiple pharmacological effects. Therefore, this study investigated neferine's role in glucose translocation to cell surface, glucose uptake, and GLUT4 expression. In our study, neferine upregulated GLUT4 expression, induced GLUT4 plasma membrane fusion, increased intracellular Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.