Evidence map›Paper›PMID 31551774›Full record

ArticleFrontiers in pharmacology2019

Screening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A.

Wenyang Wei, Haixia Du, Chongyu Shao, Huifen Zhou, Yiyu Lu, Li Yu, Haitong Wan, Yu He

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. The Activity ofInternational journal of molecular sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wenyang WeiCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Haixia DuCollege of Basic, Medical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Chongyu ShaoCollege of Life Science, Zhejiang Chinese, Medical University, Hangzhou, China.
Huifen ZhouCollege of Life Science, Zhejiang Chinese, Medical University, Hangzhou, China.
Yiyu LuInstitute of Microbiology, Zhejiang Center for Disease Control and Prevention, Hangzhou, China.
Li YuCollege of Life Science, Zhejiang Chinese, Medical University, Hangzhou, China.
Haitong WanCollege of Life Science, Zhejiang Chinese, Medical University, Hangzhou, China.
Yu HeCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CNZhejiang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Ma Huang Tang (MHT) has long been considered as a classical formula for respiratory infections like influenza, bronchitis and asthma, its chemical ingredients that really exert the main efficacy are still obscure. In this study we aimed to screen its antiviral components and investigate the potential mechanisms. The MDCK cellular research results showed that, among nine predominant ingredients of MHT, L-methylephedrin (LMEP), L-ephedrine (LEP) and D-pseudo- ephedrine (DPEP) significantly inhibited the proliferation of influenza A virus

Indexed as

Ephedra alkaloidsinflammation responseinfluenza A virusTLRs signal pathwayvirus load

Identifiers

PMID31551774
PMCPMC6747051
OpenAlexW2964412545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.