ArticleFrontiers in pharmacology2019
Ultrasound-Guided Biopsy of Pleural-Based Pulmonary Lesions by Injection of Contrast-Enhancing Drugs.
Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 31 citations in OpenAlex.
- Malignancy risk and contrast-enhanced ultrasound guidance in non-diagnostic biopsies of peripheral lung lesions: a multicenter study.European radiology · 2026Article
- Ultrasound-guided biopsy for thoracic lesions: diagnostic performance, safety, and potential role of contrast-enhanced ultrasound.Journal of medical ultrasonics (2001) · 2026Article
- The Role of CEUS in the Diagnosis and Follow-Up of Pleuropulmonary Diseases and Interventional Procedures.Journal of clinical medicine · 2026Review
- Advances in the application of different imaging techniques in percutaneous lung biopsy.Frontiers in medicine · 2026Review
- The association between core number and complications in ultrasound-guided percutaneous lung core needle biopsy for subpleural primary lung cancer: a retrospective study.BMC pulmonary medicine · 2025Article
- Comparison of the application value of contrast-enhanced ultrasound and contrast-enhanced CT in puncture biopsy of peripheral pulmonary lesions.Frontiers in oncology · 2025Article
- Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine (EFSUMB) Guidelines: Rare Malignant Pulmonal and Pleural Tumors: Primary Pulmonary Sarcoma and Mesothelioma, Imaging Features on Transthoracic Ultrasound.Diagnostics (Basel, Switzerland) · 2024Review
- [Ultrasound guided biopsy of lung tumors: evaluation of efficacy and complications].Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2023Article
- Can Ultrasound and Contrast-Enhanced Ultrasound Help Differentiate between Subpleural Focal Organizing Pneumonia and Primary Lung Malignancy?Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic Accuracy of B-Mode- and Contrast-Enhanced Ultrasound in Differentiating Malignant from Benign Pleural Effusions.Diagnostics (Basel, Switzerland) · 2021Article
- Contrast-enhanced ultrasound guided pleural biopsy improves diagnostic confidence for pleural based lesions: a 3-year prospective study.BMC pulmonary medicine · 2021Article
- Article
- Recent Advances of Organic Near-Infrared II Fluorophores in Optical Properties and Imaging Functions.Molecular imaging and biology · 2021Review
- A pictorial review of the utility of CEUS in thoracic biopsies.Insights into imaging · 2021Review
- Ultrasound-Guided Percutaneous Core Needle Biopsy of Peripheral Pulmonary Nodules ≤ 2 cm: Diagnostic Performance, Safety and Influence Factors.Frontiers in oncology · 2021Article
- Application of ultrasound in a congenital cystic adenomatoid malformation in an adult: A case report.Medicine · 2020Article
- Boundary Restored Network for Subpleural Pulmonary Lesion Segmentation on Ultrasound Images at Local and Global Scales.Journal of digital imaging · 2020Article
- Commentary: Ultrasound-Guided Biopsy of Pleural-Based Pulmonary Lesions by Injection of Contrast-Enhancing Drugs.Frontiers in pharmacology · 2020Article
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5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
In this study, a total of 58 patients with single subpleural pulmonary lesions (males: 36, females: 22, mean age: 63 ± 16.2 years) who underwent contrast-enhanced ultrasonography (CEUS) and had a definite diagnosis (benign lesions:25, malignant lesions:33) were enrolled. The number of biopsies, diagnostic accuracy rate, and the incidence of complications were recorded. The nodules were divided into two size subgroups: ≥5 cm (group 1), and <5 cm (group 2). The display rate of internal necrosis and change of pre-scheduled puncture paths were compared between subgroups. Also, the arrival times, intensity and uniformity of enhancement after the contrast agent injection, as well as the display rate of internal necrosis were recorded and compared between malignant and benign lesions. Finally, the average number of punctures was 2.9 ± 0.7 times. The total diagnosis rate was 98.3%. Local pneumothorax occurred in 2 patients. Hemoptysis occurred in 1 patient. No serious complications occurred. Internal necrosis was demonstrated in 20 of 58 lesions (34.5%). Sixteen of them had changed the planned puncture path due to the large necrosis area (80%, 16/20). For lesions in group 1, necrosis was found in 15 lesions and there was a statistically significant difference in the necrosis rate between the two subgroups (15/26 vs 5/32,
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