Evidence map›Paper›PMID 31551628›Full record

ArticleBulletin of the World Health Organization2019

Prevalence of chronic respiratory disease in urban and rural Uganda.

Trishul Siddharthan, Matthew Grigsby, Brooks Morgan, Robert Kalyesubula, Robert A Wise, Bruce Kirenga, William Checkley

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Bulletin of the World Health Organization, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05223114 (Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort), which is not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05223114 completednot on this mapstarted 2022, after this paper: background citation

Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort

TypeobservationalSponsorMakerere UniversityRan2022 to 2023Enrolled160ConditionsCOPD, HIV Infections, Respiratory DiseaseArmsNot applicable (N/A)
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. RuralEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pooled it
  3. Chronic obstructive pulmonary disease in sub-Saharan Africa.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Pooled it
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Trishul SiddharthanDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 555, Baltimore, Maryland, MD 21287, United States of America.
Matthew GrigsbyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 555, Baltimore, Maryland, MD 21287, United States of America.
Brooks MorganDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 555, Baltimore, Maryland, MD 21287, United States of America.
Robert KalyesubulaCollege of Health Sciences, Makerere University, Kampala, Uganda.
Robert A WiseDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 555, Baltimore, Maryland, MD 21287, United States of America.
Bruce KirengaCollege of Health Sciences, Makerere University, Kampala, Uganda.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 555, Baltimore, Maryland, MD 21287, United States of America.

Funding

Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
FIC NIH HHS R25 TW009340
6 · The paper itself

Abstract

objectiveTo determine the prevalence of chronic respiratory diseases in urban and rural Uganda and to identify risk factors for these diseases.

methodsThe population-based, cross-sectional study included adults aged 35 years or older. All participants were evaluated by spirometry according to standard guidelines and completed questionnaires on respiratory symptoms, functional status and demographic characteristics. The presence of four chronic respiratory conditions was monitored: chronic obstructive pulmonary disease (COPD), asthma, chronic bronchitis and a restrictive spirometry pattern.

findingsIn total, 1502 participants (average age: 46.9 years) had acceptable, reproducible spirometry results: 837 (56%) in rural Nakaseke and 665 (44%) in urban Kampala. Overall, 46.5% (698/1502) were male. The age-adjusted prevalence of any chronic respiratory condition was 20.2%. The age-adjusted prevalence of COPD was significantly greater in rural than urban participants (6.1 versus 1.5%, respectively;

conclusionThe prevalence of chronic respiratory disease was high in both rural and urban Uganda. Place of residence was the most important risk factor for COPD and asthma.

Indexed as

AdultAgedChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRespiratory Tract DiseasesRisk FactorsRural HealthUgandaUrban Health

Identifiers

PMID31551628
PMCPMC6747035

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.