Evidence map›Paper›PMID 31551514›Full record

ArticleCellular & molecular immunology2019

Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer's disease.

Pei-Pei Guan, Xin Yu, Yan-Hui Zou, Pu Wang

Abstract read
In one paragraph

Article in Cellular & molecular immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Exploring the role of COX-2 in Alzheimer's disease: Potential therapeutic implications of COX-2 inhibitors.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pei-Pei GuanCollege of Life and Health Sciences, Northeastern University, 110819, Shenyang, PR China.
Xin YuInstitute of Health Science, China Medical University, 110122, Shengyang, PR China.
Yan-Hui ZouCollege of Life and Health Sciences, Northeastern University, 110819, Shenyang, PR China.
Pu WangCollege of Life and Health Sciences, Northeastern University, 110819, Shenyang, PR China. wangpu@mail.neu.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81771167National Natural Science Foundation of China (National Science Foundation of China) 81870840National Natural Science Foundation of China (National Science Foundation of China) 81901116
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsCyclooxygenase 2Disease Models, AnimalGlycosylationMiceMice, Transgenictau ProteinsAmyloid beta-PeptidesCyclooxygenase 2Mapt protein, mousePtgs2 protein, mousetau Proteins

Identifiers

PMID31551514
PMCPMC6828724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.