ArticleScientific reports2019
Prehospital lactate improves prediction of the need for immediate interventions for hemorrhage after trauma.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The potential of point-of-care diagnostics to optimise prehospital trauma triage: a systematic review of literature.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Review
- Major Bleeding in the Emergency Department: A Practical Guide for Optimal Management.Journal of clinical medicine · 2025Review
- Added predictive value of prehospital measurement of point-of-care lactate in an adult general EMS population in Sweden: a multi-centre observational study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Observational
- Identifying trigger cues for hospital blood transfusions based on ensemble of machine learning methods.International journal of emergency medicine · 2024Article
- Identifying Trigger Cues for Hospital Blood Transfusions Based on Ensemble Learning Methods.Research square · 2024Article
- Concepts, utilization, and perspectives on the Dutch Nationwide Trauma registry: a position paper.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Review
- Prehospital predictors of the need for transfusion in patients with major trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Observational
- Accuracy of a Prehospital Triage Protocol in Predicting In-Hospital Mortality and Severe Trauma Cases among Older Adults.International journal of environmental research and public health · 2023Article
- Article
- Smart implanted access port catheter for therapy intervention with pH and lactate biosensors.Materials today. Bio · 2022Article
- The Addition of ROTEM Parameter Did Not Significantly Improve the Massive Transfusion Prediction in Severe Trauma Patients.Emergency medicine international · 2022Article
- Clinical and laboratory parameters in blunt pelvic trauma not associated with subsequent positive conventional angiography in patients with positive CTA.Emergency radiology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The blood lactate level is used to guide the management of trauma patients with circulatory disturbance. We hypothesized that blood lactate levels at the scene (Lac scene) could improve the prediction for immediate interventions for hemorrhage. We prospectively measured blood lactate levels and assessed retrospectively in 435 trauma patients both at the scene and on arrival at the emergency room (ER) of a level I trauma center. Primary outcome was immediate intervention for hemorrhage defined as surgical/radiological intervention and/or blood transfusion within 24 h. Physiological variables plus Lac scene significantly increased the predictive value for immediate intervention (area under the curve [AUC] 0.882, 95% confidence interval [CI] 0.839-0.925) compared to that using physiological variables only (AUC 0.837, 95% CI 0.787-0.887, P = 0.0073), replicated in the validation cohort (n = 85). There was no significant improvement in predicting value of physiological variables plus Lac scene for massive transfusion compared to physiological variables (AUC 0.903 vs 0.895, P = 0.32). The increased blood lactate level per minute from scene to ER was associated with increased probability for immediate intervention (P < 0.0001). Both adding Lac scene to physiological variables and the temporal elevation of blood lactate levels from scene to ER could improve the prediction of the immediate intervention.
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