Evidence map›Paper›PMID 31551387›Full record

ArticleBMJ open2019

Rationale and population-based prospective cohort protocol for the disadvantaged populations at risk of decline in eGFR (CO-DEGREE).

Marvin Gonzalez-Quiroz, Dorothea Nitsch, Sophie Hamilton, Cristina O'Callaghan Gordo, Rajiv Saran, Jason Glaser, Ricardo Correa-Rotter, Kristina Jakobsson, Ajay Singh, Nalika Gunawardena and 5 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Kidney health for everyone everywhere - from prevention to detection and equitable access to care.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 8 countries.

Marvin Gonzalez-QuirozResearch Centre on Health, Work and Environment (CISTA), National Autonomous University of Nicaragua, León, Nicaragua m.quiroz@ucl.ac.uk.ORCID 0000-0002-0093-6357
Dorothea NitschDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Sophie HamiltonSchool of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Cristina O'Callaghan GordoCampus Mar, Instituto de Salud Global Barcelona, Barcelona, Spain.
Rajiv SaranDivision of Nephrology, Department of Internal Medicine & Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Jason GlaserLa Isla Network, Washington DC, UK.
Ricardo Correa-RotterDepartment of Nephrology and Mineral Metabolism, National Medical Science and Nutrition Institute Salvador Zubirán, Mexico City, Mexico.
Kristina JakobssonDepartment of Public Health and Community Medicine, Insitute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ajay SinghBrigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Nalika GunawardenaWorld Health Organization Country Office, Colombo, Sri Lanka.
Adeera LevinDivision of Nepohrology UBC, University of British Columbia, Vancouver, British Columbia, Canada.
Giuseppe RemuzziInstituto di Ricerche Farmacologiche Mario Negri - IRCCS, Milan, Italy.
Ben Caplin *Centre for Nephrology, University College London, London, UK.ORCID 0000-0001-9544-164X
Neil Pearce *Deparment of Medical Statistics and Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
DEGREE Study Steering Committee
London School of Hygiene & Tropical Medicine · GBAction Network · USBrigham and Women's Hospital · USImperial College London · GBInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXMario Negri Institute for Pharmacological Research · ITNational Autonomous University of Nicaragua · NISahlgrenska University Hospital · SEUniversitat Pompeu Fabra · ESUniversity College London · GBUniversity of British Columbia · CAUniversity of Michigan · US

Funding

Medical Research Council MR/P02386X/1World Health Organization 001
6 · The paper itself

Abstract

introductionA recently recognised form of chronic kidney disease (CKD) of unknown origin (CKDu) is afflicting communities, mostly in rural areas in several regions of the world. Prevalence studies are being conducted in a number of countries, using a standardised protocol, to estimate the distribution of estimated glomerular filtration rate (eGFR), and thus identify communities with a high prevalence of reduced glomerular filtration rate (GFR). In this paper, we propose a standardised minimum protocol for cohort studies in high-risk communities aimed at investigating the incidence of, and risk factors for, early kidney dysfunction. METHODS AND ANALYSIS: This generic cohort protocol provides the information to establish a prospective population-based cohort study in low-income settings with a high prevalence of CKDu. This involves a baseline survey that included key elements from the DEGREE survey (eg, using the previously published DEGREE methodology) of a population-representative sample, and subsequent follow-up visits in young adults (without a pre-existing diagnosis of CKD (eGFR<60 mL/min/1.73m ETHICS AND DISSEMINATION: Ethical approval will be obtained by local researchers, and participants will provide informed consent before the study commences. Participants will typically receive feedback and advice on their laboratory results, and referral to a local health system where appropriate.

Indexed as

Glomerular Filtration RateKidney Failure, ChronicProteinuriaRenal Insufficiency, ChronicRisk AssessmentClinical Studies as TopicCohort StudiesDisease ProgressionFemaleHealth Services Needs and DemandHumansInternational CooperationMalePrevalenceResearch DesignRisk Factorschronic kidney disease of unknown aetiologydecline in kidney functiongeneric cohort protocolprospective cohort study

Identifiers

PMID31551387
PMCPMC6773312
OpenAlexW2976709722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.