Evidence map›Paper›PMID 31551351›Full record

ArticleThe Journal of biological chemistry2019

Analyses of epithelial Na

Xueqi Wang, Jingxin Chen, Shujie Shi, Shaohu Sheng, Thomas R Kleyman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Epithelial Na+ Channels, Immune Cells, and Salt.Annual review of physiology · 2025
    Review
  2. Epithelial NaComprehensive Physiology · 2024
    Review
  3. Article
  4. Rare Variants in Genes Encoding Subunits of the Epithelial NaHypertension (Dallas, Tex. : 1979) · 2022
    Article
  5. Epithelial Sodium Channel and Salt-Sensitive Hypertension.Hypertension (Dallas, Tex. : 1979) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xueqi WangRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Jingxin ChenRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Shujie ShiRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Shaohu ShengRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 shaohu@pitt.edu.ORCID 0000-0002-7198-1702
Thomas R KleymanRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.ORCID 0000-0002-2413-5415

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
ENaC regulation and its role in blood pressure homeostasisR01HL147818 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Annet Kirabo, Thomas R Kleyman · 2019 to 2026
$4.6M
Regulation of ENaC/degenerin channels by mechanical forcesK01DK103834 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHI, SHUJIE · 2014 to 2018
$688k
Regulation of ENaC expression by paraoxonase-2R03DK119752 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHI, SHUJIE · 2019 to 2020
$235k
NHLBI NIH HHS R01 HL147818NIDDK NIH HHS K01 DK103834NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R03 DK119752
6 · The paper itself

Abstract

Epithelial Na

Indexed as

Epithelial Sodium ChannelsExtracellular SpaceGene Expression RegulationHumansIon Channel GatingModels, MolecularProtein DomainsEpithelial Sodium Channelsacid-sensing ion channel (ASIC)amilorideblood pressuredegenerinepithelial sodium channel (ENaC)genetic polymorphismNa+ self-inhibitionnonvoltage-gated ion channelpatch clampXenopus

Identifiers

PMID31551351
PMCPMC6851303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.