Evidence map›Paper›PMID 31551334›Full record

ArticlemBio2019

Porphyromonas gingivalis Tyrosine Phosphatase Php1 Promotes Community Development and Pathogenicity.

Young-Jung Jung, Daniel P Miller, John D Perpich, Zackary R Fitzsimonds, Daonan Shen, Jun Ohshima, Richard J Lamont

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Tyrosine phosphorylation coupling of one-carbon metabolism and virulence in an endogenous pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. One-carbon metabolism and microbial pathogenicity.Molecular oral microbiology · 2024
    Review
  7. The polymicrobial pathogenicity ofFrontiers in oral health · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. International journal of molecular sciences · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Quantification of Human Oral and FecalFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Young-Jung JungDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Daniel P MillerDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
John D PerpichDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Zackary R FitzsimondsDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Daonan ShenDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Jun OhshimaDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Richard J LamontDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA rich.lamont@louisville.edu.ORCID 0000-0002-3147-5039
University of Louisville · US

Funding

MOLECULAR ASPECTS OF ORAL PLAQUE FORMATIONR01DE012505 · NIDCR · UNIVERSITY OF WASHINGTON · PI Richard J Lamont, JAN S POTEMPA · 1998 to 2026
$9.5M
P GINGIVALIS INTERACTIONS WITH GINGIVAL EPITHELIAL CELLSR01DE011111 · NIDCR · UNIVERSITY OF WASHINGTON · PI HARIBABU BODDULURI, Richard J Lamont · 1995 to 2026
$5.4M
Probing Polymicrobial Synergy Using hihg Throughout GenomicsR01DE023193 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI LAMONT, RICHARD J, WHITELEY, MARVIN · 2013 to 2023
$4.7M
P.gingivalis Interactions with Gingival Epithelial CellsR37DE011111 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2009 to 2018
$3.6M
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisR00DE028346 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILLER, DANIEL PATRICK · 2020 to 2022
$747k
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisK99DE028346 · NIDCR · UNIVERSITY OF LOUISVILLE · PI MILLER, DANIEL PATRICK · 2018 to 2019
$214k
Regulation of ZEB1 by Porphyromonas gingivalis in gingival epithelial cellsF30DE028166 · NIDCR · UNIVERSITY OF LOUISVILLE · PI FITZSIMONDS, ZACKARY R · 2018 to 2021
$150k
Phosphotyrosine Signaling of Porphyromonas gingivalisF32DE026939 · NIDCR · UNIVERSITY OF LOUISVILLE · PI MILLER, DANIEL PATRICK · 2017 to 2018
$96k
NIDCR NIH HHS F30 DE028166NIDCR NIH HHS F32 DE026939NIDCR NIH HHS K99 DE028346NIDCR NIH HHS R00 DE028346NIDCR NIH HHS R01 DE011111NIDCR NIH HHS R01 DE012505NIDCR NIH HHS R01 DE023193NIDCR NIH HHS R37 DE011111
6 · The paper itself

Abstract

Protein-tyrosine phosphorylation in bacteria plays a significant role in multiple cellular functions, including those related to community development and virulence. Metal-dependent protein tyrosine phosphatases that belong to the polymerase and histindinol phosphatase (PHP) family are widespread in Gram-positive bacteria. Here, we show that

Indexed as

Bacterial LoadBacterial Physiological PhenomenaHumansPorphyromonas gingivalisProtein Tyrosine PhosphatasesVirulenceProtein Tyrosine Phosphatasesmicrobial communitiesperiodontitistyrosine phosphatase

Identifiers

PMID31551334
PMCPMC6759763
OpenAlexW2975271082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.