Evidence map›Paper›PMID 31551286›Full record

ArticleG3 (Bethesda, Md.)2019

Genome-Wide Analysis of Cell Cycle-Regulating Genes in the Symbiotic Dinoflagellate

Michael L Cato, Hallie D Jester, Adam Lavertu, Audrey Lyman, Lacey M Tallent, Geoffrey C Mitchell

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Stability of the cnidarian-dinoflagellate symbiosis is primarily determined by symbiont cell-cycle arrest.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael L CatoDepartment of Biology, Wofford College, Spartanburg, SC, 29303 and.
Hallie D JesterDepartment of Biology, Colby College, Waterville, ME, 04901.
Adam LavertuDepartment of Biology, Colby College, Waterville, ME, 04901.
Audrey LymanDepartment of Biology, Colby College, Waterville, ME, 04901.
Lacey M TallentDepartment of Biology, Wofford College, Spartanburg, SC, 29303 and.
Geoffrey C MitchellDepartment of Biology, Wofford College, Spartanburg, SC, 29303 and mitchellgc@wofford.edu.ORCID 0000-0002-4149-3564

Funding

Biomedical Data Science Graduate Training at StanfordT32LM012409 · NLM · STANFORD UNIVERSITY · PI PLEVRITIS, SYLVIA KATINA · 2016 to 2020
$1.5M
NLM NIH HHS T32 LM012409
6 · The paper itself

Abstract

A delicate relationship exists between reef-building corals and their photosynthetic endosymbionts. Unfortunately, this relationship can be disrupted, with corals expelling these algae when temperatures rise even marginally above the average summer maximum. Interestingly, several studies indicate that failure of corals to regulate symbiont cell divisions at high temperatures may underlie this disruption; increased proliferation of symbionts may stress host cells by over-production of reactive oxygen species or by disrupting the flow of nutrients. This needs to be further investigated, so to begin deciphering the molecular mechanisms controlling the cell cycle in these organisms, we used a computational approach to identify putative cell cycle-regulating genes in the genome of the dinoflagellate

Indexed as

AnimalsCell CycleCyclin-Dependent KinasesDinoflagellidaGenomePhylogenySea AnemonesSymbiosisCyclin-Dependent KinasesAiptasiaBreviolumcell cyclecyclin-dependent kinasescyclinsdinoflagellateSymbiodiniaceaeSymbiodinium

Identifiers

PMID31551286
PMCPMC6829154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.