Evidence map›Paper›PMID 31550995›Full record

ArticleMolecular pain

Rat Na

B Grubinska, L Chen, M Alsaloum, N Rampal, D J Matson, C Yang, K Taborn, M Zhang, B Youngblood, D Liu and 10 more

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. NaThe Journal of comparative neurology · 2026
    Article
  2. Modulation of human dorsal root ganglion neuron firing by the Nav1.8 inhibitor suzetrigine.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Inhibition of NaRSC medicinal chemistry · 2022
    Review
  11. The HumanFrontiers in molecular neuroscience · 2022
    Article
  12. Article
  13. Antitussive effects of NaEuropean journal of pharmacology · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Case Report: MutantFrontiers in neuroscience · 2021
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

B GrubinskaNeuroscience Department, Amgen Research, Cambridge, MA, USA.
L ChenDepartment of Neurology, Yale University, New Haven, CT, USA.
M AlsaloumDepartment of Neurology, Yale University, New Haven, CT, USA.ORCID 0000-0002-9832-0138
N RampalNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
D J MatsonNeuroscience Department, Amgen Research, Cambridge, MA, USA.ORCID 0000-0003-4791-8866
C YangNeuroscience Department, Amgen Research, Cambridge, MA, USA.
K TabornNeuroscience Department, Amgen Research, Cambridge, MA, USA.
M ZhangNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
B YoungbloodNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
D LiuNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
E GalbreathComparative Biology and Safety Sciences, Amgen Research, Cambridge, MA, USA.
S AllredComparative Biology and Safety Sciences, Amgen Research, South San Francisco, CA, USA.
M LepherdComparative Biology and Safety Sciences, Amgen Research, South San Francisco, CA, USA.
R FerrandoComparative Biology and Safety Sciences, Amgen Research, South San Francisco, CA, USA.
T J KornecookNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
S G LehtoNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
S G WaxmanDepartment of Neurology, Yale University, New Haven, CT, USA.
B D MoyerNeuroscience Department, Amgen Research, Thousand Oaks, CA, USA.
S Dib-HajjDepartment of Neurology, Yale University, New Haven, CT, USA.
J GingrasNeuroscience Department, Amgen Research, Cambridge, MA, USA.
Amgen (United States) · USYale University · USBiogen (United States) · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesAnimalsBinding SitesFemaleGenotypeHumansMaleNAV1.7 Voltage-Gated Sodium ChannelNerve FibersNeuralgiaPhenotypeRatsSciatic NerveNAV1.7 Voltage-Gated Sodium ChannelScn9a protein, ratanti-NaV1.7 antibodyNaV1.7 voltage-gated sodium channelNeuropathic painnociceptionrat knockinSCN9A

Identifiers

PMID31550995
PMCPMC6831982
OpenAlexW2975093794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.