ArticleJournal of the American Heart Association2019
Association Between Occupational Exposure to Pesticides and Cardiovascular Disease Incidence: The Kuakini Honolulu Heart Program.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Insights into Organochlorine Pesticides Exposure in the Development of Cardiovascular Diseases: A Systematic Review.Archives of Iranian medicine · 2023Pooled it
- Associations Between Urinary Pesticide Metabolites and Serum Inflammatory Biomarkers in Adolescents Living in an Agricultural Region.Exposure and health · 2025Article
- Pesticide exposure and cardiovascular health in non-CVD mortality population: novel evidence from NHANES 2007-2018 using Life's Essential 8.Frontiers in nutrition · 2025Article
- Is Farming a Risk Occupation for Cardio-cerebrovascular Diseases? A Scoping Review on Cardio-cerebrovascular Disease Risk in Farmers.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Article
- Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication.ACS pharmacology & translational science · 2024Review
- Personal Strategies to Reduce the Cardiovascular Impacts of Environmental Exposures.Circulation research · 2024Review
- Environmental endocrine disruptor-induced mitochondrial dysfunction: a potential mechanism underlying diabetes and its complications.Frontiers in endocrinology · 2024Review
- Article
- Pollutants, including Organophosphorus and Organochloride Pesticides, May Increase the Risk of Cardiac Remodeling and Atrial Fibrillation: A Narrative Review.Biomedicines · 2023Review
- Investigating the relationship between non-occupational pesticide exposure and metabolomic biomarkers.Frontiers in public health · 2023Article
- Association of Pulmonary Function With Motor Function Trajectories and Disability Progression Among Older Adults: A Long-Term Community-Based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Synergistic action of organophosphates and COVID-19 on inflammation, oxidative stress, and renin-angiotensin system can amplify the risk of cardiovascular maladies.Toxicology and applied pharmacology · 2022Article
- Social and environmental risks as contributors to the clinical course of heart failure.Heart failure reviews · 2022Review
- Determinants of Hypertension amongst Rice Farmers in West Java, Indonesia.International journal of environmental research and public health · 2022Article
- Role of environmental toxicants in the development of hypertensive and cardiovascular diseases.Toxicology reports · 2022Review
- Angiotensin II type 1 receptor is involved in hypertension and vascular alterations caused by environmental toxicant hexachlorobenzene.Toxicology reports · 2021Article
- Prospective association between organic food consumption and the risk of type 2 diabetes: findings from the NutriNet-Santé cohort study.The international journal of behavioral nutrition and physical activity · 2020Article
- Longitudinal Study of Metabolic Biomarkers among Conventional and Organic Farmers in Thailand.International journal of environmental research and public health · 2020Article
- Association Between Occupational Exposure to Pesticides and Cardiovascular Disease Incidence: The Kuakini Honolulu Heart Program.Journal of the American Heart Association · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Background Previously, Kuakini Honolulu Heart Program researchers reported that occupational exposure to pesticides was significantly associated with total mortality. The current study examines occupational exposure to pesticides in relation to incident cardiovascular disease, defined as coronary heart disease or cerebrovascular accident. Methods and Results With the Occupational Safety Health Administration exposure scale used as an estimate of exposure, statistical analyses were performed on a cohort of 7557 Japanese-American men from the Kuakini Honolulu Heart Program. Hazard ratios for cardiovascular disease incidence were calculated for various levels of pesticide exposure using Cox proportional hazards models. In the first 10 years of follow-up, a positive association was observed between age-adjusted cardiovascular disease incidence and high levels of pesticide exposure (hazard ratio=1.46, 95% CI=1.10-1.95,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.