Evidence map›Paper›PMID 31550294›Full record

ArticlePloS one2019

Incidence of retinal vein occlusion with long-term exposure to ambient air pollution.

Han-Wei Zhang, Chao-Wen Lin, Victor C Kok, Chun-Hung Tseng, Yuan-Pei Lin, Tsai-Chung Li, Fung-Chang Sung, Chi Pang Wen, Chao A Hsiung, Chung Y Hsu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Chronic ambient air pollution and the incidence of blepharitis and blepharoconjunctivitis: a nationwide population-based cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Review
  3. Article
  4. Retinal toxicity of heavy metals and its involvement in retinal pathology.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Han-Wei ZhangPhD Program for Aging, China Medical University, Taichung, Taiwan.ORCID 0000-0001-8999-8492
Chao-Wen LinDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Victor C KokDisease Informatics Research Group, Asia University Taiwan, Taichung, Taiwan.
Chun-Hung TsengDepartment of Neurology, China Medical University Hospital, and School of Medicine, China Medical University, Taichung, Taiwan.
Yuan-Pei LinInstitute of Electrical Control Engineering, Department of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu, Taiwan.
Tsai-Chung LiGraduate Institute of Biostatistics, College of Public Health, China Medical University, Taichung, Taiwan.
Fung-Chang SungGraduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Chi Pang WenInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Chao A HsiungInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Chung Y HsuGraduate Institute of Biomedical Science, China Medical University, Taichung, Taiwan.
China Medical University · TWAsia University · TWNational Health Research Institutes · TWNational Yang Ming Chiao Tung University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate whether long-term exposure to airborne hydrocarbons, including volatile organic compounds, increases the risk of developing retinal vein occlusion (RVO) among the population of Taiwan. A retrospective cohort study involving 855,297 people was conducted. Cox proportional hazards regression analysis fitted the multiple pollutant models for two targeted pollutants, including total hydrocarbons (THC), nonmethane hydrocarbons (NMHC) were used, and the risk of RVO was estimated. The chi-squared test and one-way analysis of variance were used to test differences in demographics and comorbidity distribution among tertiles of the targeted pollutants. Before controlling for multiple pollutants, hazard ratios for the overall population were 19.88 (95% CI: 17.56-22.50) at 0.51-ppm increases in THC and 4.33 (95% CI: 3.97-4.73) at 0.27-ppm increases in NMHC. The highest adjusted hazard ratios for different multiple pollutant models of each targeted pollutant were statistically significant (all p values were ≤0.05) for all patients at 29.67 (95% CI: 25.57-34.42) for THC and 16.24 (95% CI: 14.14-18.65) for NMHC. Our findings suggest that long-term exposure to THC and NMHC contribute to RVO development.

Indexed as

AdolescentAdultAir PollutantsAir PollutionChildDatabases, FactualFemaleHumansHydrocarbonsIncidenceMaleMiddle AgedProportional Hazards ModelsRetinal Vein OcclusionRetrospective StudiesRisk FactorsAir PollutantsHydrocarbons

Identifiers

PMID31550294
PMCPMC6759191
OpenAlexW2974954484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.