Evidence map›Paper›PMID 31550051›Full record

Trial reportCancer2020

Developing efficient and effective behavioral treatment for insomnia in cancer survivors: Results of a stepped care trial.

Eric S Zhou, Alexis L Michaud, Christopher J Recklitis

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  6. Sleep health and quality of life in the Detroit Research on Cancer Survivors cohort.Journal of cancer survivorship : research and practice · 2025
    Article
  7. Application of stepped care model in cancer patients: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  13. Winner of the Ronald Melzack-Canadian journal of pain = Revue canadienne de la douleur · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eric S ZhouPerini Family Survivors' Center, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0003-1038-8961
Alexis L MichaudPerini Family Survivors' Center, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-1163-2711
Christopher J RecklitisPerini Family Survivors' Center, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0003-1336-8261
Harvard University · USDana-Farber Cancer Institute · US

Funding

CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer SurvivorsR03CA201459 · NCI · DANA-FARBER CANCER INST · PI RECKLITIS, CHRISTOPHER JOHN · 2016 to 2017
$175k
NCI NIH HHS R03 CA201459
6 · The paper itself

Abstract

backgroundInsomnia is common among cancer survivors. Although behavioral treatments for insomnia are effective, access is limited. Stepped care delivery models may provide insomnia treatment that is more efficient and accessible to cancer survivors.

methodsFifty-one survivors (mean age, 55 years) with elevated Insomnia Severity Index (ISI) scores (≥12) first participated in Sleep Training Education Program (STEP)-1: a single, sleep education session. Those reporting elevated ISI scores 1 month later were offered STEP-2: a 3-session, group cognitive behavioral treatment for insomnia that has been demonstrated to be efficacious. Participants were considered treatment responders if their ISI score improved by ≥6 points and were considered as having remitted if their posttreatment ISI score was <12. Mood was assessed with the Profile of Mood States-Short Form (POMS-SF).

resultsFollowing STEP-1, ISI scores improved (17.1 to 11.2; P < .001), with 45% responding and 41% remitted. Insomnia remission after STEP-1 was associated with lower insomnia severity and shorter duration of sleep problems at baseline. Of the 30 (59%) survivors with unremitted insomnia after STEP-1, 14 (47%) participated in STEP-2. Following STEP-2, ISI scores improved (16.9 to 8.8; P < .001), with 79% responding and 71% remitted. STEP-2 participation was associated with interest in sleep treatment at baseline, but not demographic/health-related variables. Mood improved significantly following both STEP-1 and STEP-2 (P < .001).

conclusionA stepped care approach to treating insomnia among cancer survivors has the potential to improve treatment accessibility. A sizable proportion of survivors can benefit from 2 different low-intensity approaches that could be delivered by nonsleep specialists. For individuals who require more intensive care, assessing treatment interest can identify those who are likely to engage.

Indexed as

AdultCancer SurvivorsCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedNeoplasmsSeverity of Illness IndexSleepSleep Initiation and Maintenance DisordersSleep Wake DisordersTreatment Outcomecancer survivorcognitive-behavioral therapy for insomniainsomniastepped care

Identifiers

PMID31550051
PMCPMC6906236
OpenAlexW2975215189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.