Evidence map›Paper›PMID 31550044›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Viral Blips After Treatment Initiation During Acute Human Immunodeficiency Virus Infection.

Trevor A Crowell, Suteeraporn Pinyakorn, Carlo Sacdalan, Eugène Kroon, Donn J Colby, Suwanna Puttamaswin, Sasiwimol Ubolyam, Rapee Trichavaroj, Oratai Butterworth, Ellen Turk and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Cytomegalovirus "Blips" and Rates of Progression to Clinically Significant CMV in Cardiothoracic Transplant Recipients.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Trevor A CrowellUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Suteeraporn PinyakornUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Carlo SacdalanSouth East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Eugène KroonSouth East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Donn J ColbySouth East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Suwanna PuttamaswinSouth East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Sasiwimol UbolyamThe HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Rapee TrichavarojArmed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Oratai ButterworthUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Ellen TurkUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Corinne McculloughUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Nicolas ChomontCentre de Recherche du Centre Hospitalier de l'Université de Montréal and Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Quebec, Canada.
Mark de SouzaHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
Merlin L RobbUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Nittaya PhanuphakSouth East Asia Research Collaboration in HIV, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Jintanat AnanworanichUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
RV254/SEARCH010 Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient viral blips ≥20 copies/mL were observed in 16.9% of acutely treated adults with HIV. Blip incidence increased from 0.0 (95% CI, 0.0-2.9)/100 person-years after ART in Fiebig I to 15.9 (7.6-29.2) in Fiebig V. Increasing viral load and Fiebig stage at ART initiation were independently predictive of blips.

Indexed as

HIV-1HIV InfectionsAdultAntiretroviral Therapy, Highly ActiveHumansViral Loadacquired immunodeficiency syndromeanti-HIV agentsantiretroviral agentsThailandviremia

Identifiers

PMID31550044
PMCPMC7286371

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.