Evidence map›Paper›PMID 31549581›Full record

ReviewJournal of the American Heart Association2019

Sex Differences in Cardiovascular Disease and Cognitive Impairment: Another Health Disparity for Women?

Annabelle Santos Volgman, C Noel Bairey Merz, Neelum T Aggarwal, Vera Bittner, T Jared Bunch, Philip B Gorelick, Pauline Maki, Hena N Patel, Athena Poppas, Jeremy Ruskin and 5 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04838249 (Investigation of the Effects of Testosterone and Estrogen on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System in Transsexual Patients Undergoing Cross-sex Hormone Therapy), which is not on this map. Cited by 53 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04838249 recruitingnot on this mapstarted 2021, after this paper: background citation

Investigation of the Effects of Testosterone and Estrogen on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System in Transsexual Patients Undergoing Cross-sex Hormone Therapy

TypeobservationalSponsorUniversity of LeipzigRan2021 to 2026Enrolled80ConditionsTranssexualism, Transgenderism, Adiposity, Eating Behavior
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. A multidomain trial for cognition in women with cardiovascular disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Frontiers in global women's health · 2025
    Article
  17. Review
  18. Interactive Relations of Body Mass Index, Cardiorespiratory Fitness, and Sex to Cognitive Function in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Annabelle Santos VolgmanSection of Cardiology Department of Medicine Rush Medical College Chicago IL.
C Noel Bairey MerzBarbra Streisand Women's Heart Center Smidt Heart Institute Cedars-Sinai Medical Center Los Angeles CA.
Neelum T AggarwalDepartments of Neurological Sciences Rush Alzheimer's Disease Center Rush Medical College Chicago IL.
Vera BittnerDivision of Cardiovascular Disease Department of Medicine University of Alabama at Birmingham AL.
T Jared BunchSection of Cardiology Department of Medicine Stanford University Palo Alto California.
Philip B GorelickDepartment of Translational Neuroscience Michigan State University College of Human Medicine Grand Rapids MI.
Pauline MakiDepartment of Psychiatry, Psychology and Obstetrics & Gynecology University of Illinois at Chicago IL.
Hena N PatelSection of Cardiology Department of Medicine Rush Medical College Chicago IL.
Athena PoppasSection of Cardiology Department of Medicine Brown University School of Medicine Providence RI.
Jeremy RuskinDivision of Cardiology Massachusetts General Hospital Boston MA.
Andrea M RussoSection of Cardiology Department of Medicine Cooper Medical School of Rowan University Camden NJ.
Shari R WaldsteinDepartment of Psychology University of Maryland, Baltimore County Baltimore MD.
Nanette K WengerSection of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA.
Kristine YaffeDepartment of Psychiatry, Neurology and Epidemiology University of California San Francisco San Francisco CA.
Carl J PepineDivision of Cardiovascular Medicine Department of Medicine University of Florida Gainesville FL.

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesWomen's HealthAdultAgedAge FactorsCardiovascular DiseasesCardiovascular SystemCognitionCognitive DysfunctionFemaleHumansMaleMiddle AgedPrognosisRisk AssessmentAlzheimer diseaseAPOEcardiac procedurescomplicationdementiaischemic heart diseasestrokes

Identifiers

PMID31549581
PMCPMC6806032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.