Evidence map›Paper›PMID 31549324›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2019

Pooled data analysis of primary ventral (PVH) and incisional hernia (IH) repair is no more acceptable: results of a systematic review and metanalysis of current literature.

C Stabilini, G Cavallaro, P Dolce, S Capoccia Giovannini, F Corcione, M Frascio, M Sodo, G Merola, U Bracale

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Robotic-assisted ventral hernia repair - a detailed economic evaluation: is it worth it?Hernia : the journal of hernias and abdominal wall surgery · 2025
    Trial
  10. Article
  11. Review
  12. Review
  13. Article
  14. Mapping the therapeutic landscape in emergency incisional hernia: a scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  15. Complex abdomen: a scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  16. ENGINE-An EHS Project for Future Guidelines.Journal of abdominal wall surgery : JAWS · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C StabiliniDepartment of Surgical Science, University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
G CavallaroGeneral and Laparoscopic Surgery Unit, Department of Surgery "P. Valdoni", Sapienza University, Rome, Italy. giuseppe.cavallaro@uniroma.it.ORCID http://orcid.org/0000-0001-7121-2295
P DolceDepartment of Public Health, Federico II University, Naples, Italy.
S Capoccia GiovanniniDepartment of Surgical Science, University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
F CorcioneDepartment of Public Health, Federico II University, Naples, Italy.
M FrascioDepartment of Surgical Science, University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
M SodoDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
G MerolaDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
U BracaleDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrimary (PVHs) and incisional (IHs) ventral hernias represent a common indication for surgery. Nevertheless, most of the papers presented in literature analyze both types of defect together, thus potentially introducing a bias in the results of interpretation. The purpose of this systematic review and meta-analysis is to highlight the differences between these two entities.

methodsMethods MEDLINE, Scopus, and Web of Science databases were reviewed to identify studies evaluating the outcomes of both open and laparoscopic repair with mesh of PVHs vs IHs. Search was restricted to English language literature. Risk of bias was assessed with MINORS score. Primary outcome was recurrence, and secondary outcomes were baseline characteristics and intraoperative and postoperative data. Fixed effects model was used unless significant heterogeneity, assessed with the Higgins I square (I

resultsThe search resulted in 783 hits, after screening; 11 retrospective trials were selected including 38,727 patients. Mean MINORS of included trials was 15.2 (range 5-21). The estimated pooled proportion difference for recurrence was - 0.09 (- 0.11; - 0.07) between the two groups in favor of the PVH group. On metanalysis, PVHs were smaller in area and diameters, affected younger and less comorbid patients, and were more frequently singular; the operative time and length of stay was quicker. Other complications did not differ significantly.

conclusionOur paper supports the hypothesis that PVH and IH are different conditions with the latter being more challenging to treat. Accordingly, EHS classifications should be adopted systematically as well as pooling data analysis should be no longer performed in clinical trials.

Indexed as

Hernia, VentralHerniorrhaphyIncisional HerniaOutcome and Process Assessment, Health CareData AnalysisHumansAbdominal wall hernia classificationAbdominal wall repairIncisional herniaMesh repairPooled analysisPrimary ventral hernia

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.