Trial reportEuropean child & adolescent psychiatry2020
Cooperative parent-mediated therapy for Italian preschool children with autism spectrum disorder: a randomized controlled trial.
Trial report in European child & adolescent psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Cooperative Group Therapy in Adolescents With Fragile X Syndrome (FXS) and in Adolescents With Autism Spectrum Disorder (ASD)
Evaluation of the Clinical Efficacy of Cooperative Parent-Mediated Therapy (Cooperative-PMT) in Preschool and School-Aged Children With ASD Within the "Autism in Re.Te: Let's Not Leave Them Alone" - Social Project
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Comparison of the efficacy of parent-mediated NDBIs on developmental skills in children with ASD and fidelity in parents: a systematic review and network meta-analysis.BMC pediatrics · 2024Pooled it
- Effects of Parent-Implemented Interventions on Outcomes of Children with Autism: A Meta-Analysis.Journal of autism and developmental disorders · 2023Pooled it
- Psychological interventions targeting mental health and the mother-child relationship in autism: Systematic review and meta-analysis.Developmental medicine and child neurology · 2023Pooled it
- Parent-Mediated Interventions for Children and Adolescents With Autism Spectrum Disorders: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Mapping the landscape of early childhood development services: a global scoping review.BMJ open · 2026Article
- Parental Stress and Caregiver Role Modulate Child-Caregiver Prosodic Synchrony in Autism: A Computational Analysis.Autism research : official journal of the International Society for Autism Research · 2026Article
- Feasibility of an Evidence-Based Parent-Mediated Intervention for Autism Spectrum Disorder in a Community Healthcare Service in Italy.Children (Basel, Switzerland) · 2025Article
- Cooperative parent mediated therapy for Italian children with autism spectrum disorder: a clinical experimental study in a community healthcare service in Italy.Frontiers in child and adolescent psychiatry · 2025Article
- Exploring the clinical features of minimally verbal autistic children.Frontiers in psychiatry · 2025Article
- HERVs Endophenotype in Autism Spectrum Disorder: Human Endogenous Retroviruses, Specific Immunoreactivity, and Disease Association in Different Family Members.Microorganisms · 2024Review
- Changes in Caregiver Outcomes After Participation in the Engaged Eaters Program: A Caregiver-Mediated Feeding Intervention for Autistic Children and Their Families.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2024Article
- The Efficacy of Early Interventions for Children with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Pragmatic Profiles of Adults with Fragile X Syndrome and Williams Syndrome.Brain sciences · 2022Article
- Risk and protective factors of quality of life for children with autism spectrum disorder and their families during the COVID-19 lockdown. An Italian study.Research in developmental disabilities · 2022Article
- Effectiveness of parent-training program on children with autism spectrum disorder in China.International journal of developmental disabilities · 2022Article
- Cooperative Parent-Mediated Therapy in Children with Fragile X Syndrome and Williams Beuren Syndrome: A Pilot RCT Study of a Transdiagnostic Intervention-Preliminary Data.Brain sciences · 2021Article
- Psychometric Properties of the Standardised Instruments that are Used to Measure (Pragmatic) Intervention Effects in Autistic Children: A Systematic Review.Autism & developmental language impairmentsReview
- Neurodevelopmental outcomes of infants of diabetic mothers.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on social communication skills, but with a wide heterogeneity that requires further research. In this randomized controlled trial (RCT), cooperative parent-mediated therapy (CPMT) an individual parent coaching program for young children with ASD was administered to preschool children with ASD. All children received the same low-intensity psychosocial intervention (LPI) delivered in community settings, to evaluate the potential additional benefit of CPMT. Thirty-four participants with ASD (7 females; 27 males; aged 2, 6, 11 years) and their parents were included in the trial. The primary blinded outcome was social communication skills, assessed using the ADOS-G social communication algorithm score (ADOS-G SC). Secondary outcomes included ASD symptom severity, parent-rated language abilities and emotional/behavioral problems, and self-reported caregiver stress. Evaluations were made at baseline and post-treatment (at 6 months) by an independent multidisciplinary team. Results documented that CPMT showed an additional benefit on LPI with significant improvements of the primary blinded outcome, socio-communication skills, and of some secondary outcomes such as ASD symptom severity, emotional problems and parental stress related to parent-child dysfunctional interaction. No additional benefit was found for language abilities. Findings of our RCT show that CPMT provide an additional significant short-term treatment benefit on ASD core symptoms, when compared with active control group receiving only LPI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.