ArticleJournal of family medicine and primary care2019
Determination of antifungal minimum inhibitory concentration and its clinical correlation among treatment failure cases of dermatophytosis.
Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- In vitro antifungal resistance and molecular analysis of the SQLE gene in dermatophytosis: a laboratory-based study.Iranian journal of microbiology · 2026Article
- Does the use of topical azoles have an impact on antifungal resistance?The Journal of antimicrobial chemotherapy · 2025Article
- Development and Characterization of Polymeric Films Loaded with Terbinafine for Fungal Infection Treatment.Polymers · 2025Article
- Multidrug-resistant keratinolytic dermatophytes and non-dermatophytes causing onychomycosis in outpatients.Future microbiology · 2025Article
- Clinical and Microbiological Spectrum of Dermatophytosis From a Tertiary Care Institute.Cureus · 2025Article
- Antifungal Patterns of Dermatophytes: A Pathway to Antifungal Stewardship in Eastern India.Cureus · 2024Article
- Bisphosphonates synergistically enhance the antifungal activity of azoles in dermatophytes and other pathogenic molds.mSphere · 2024Article
- New Teixobactin Analogues with a Total Lactam Ring.ACS medicinal chemistry letters · 2023Article
- Comparative analysis of whole genomes and transcriptomes ofEmerging microbes & infections · 2023Article
- Comparison of in vitro activities of newer triazoles and classic antifungal agents against dermatophyte species isolated from Iranian University Hospitals: a multi-central study.Annals of clinical microbiology and antimicrobials · 2023Article
- Laboratory Diagnosis and In Vitro Antifungal Susceptibility ofAntibiotics (Basel, Switzerland) · 2022Article
- Article
- Molecular Epidemiology and Antifungal Susceptibility ofJournal of fungi (Basel, Switzerland) · 2021Article
- Regional Differences in Antifungal Susceptibility of the Prevalent Dermatophyte Trichophyton rubrum.Mycopathologia · 2021Article
- Population differentiation, antifungal susceptibility, and host range of Trichophyton mentagrophytes isolates causing recalcitrant infections in humans and animals.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Comparative Analysis ofIndian journal of dermatologyArticle
- Topical Itraconazole Formulations: Unscrupulous Pharmaceutical Companies and Lax Indian Drug Regulators Endangering a Precious Drug.Indian dermatology online journalArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDermatophytes are most common infectious agents causing superficial mycosis worldwide. A number of topical as well as systemic antifungal drugs are available for treatment of dermatophytosis. Superficial mycosis caused by dermatophytes can be easily treated by topical or oral antifungal drugs, but in the course of time, an increased number of treatment failure cases are appearing. Possible cause for treatment failure could be poor patient compliance, poor drug penetration into affected lesion, and also drug resistance in dermatophytes. The aim of this study is to investigate minimum inhibitory concentration and clinical correlation in treatment failure cases of dermatophytosis.
methodsSkin, hair and nail samples were collected from treatment failure cases of dermatophytosis. A total 75 isolates were tested for MIC against four antifungal drugs in the study. Fluconazole, itraconazole, ketoconazole and terbinafine were the antifungal drugs tested using broth microdilution method. MIC
resultsA total of 75 dermatophytic isolates were tested. Dermatophytic isolates in this study were Trichophyton mentagrophytes (
conclusionMIC of 17.33% isolates for fluconazole and 33.33% isolates for terbinafine were lower than cut-off value, which indicates that not all treatment failure cases are due to drug resistance.
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