Evidence map›Paper›PMID 31548924›Full record

ArticleJournal of microscopy and ultrastructure

Immunohistochemical Expression of Myofibroblasts Using Alpha-smooth Muscle Actin (SMA) to Assess the Aggressive Potential of Various Clinical Subtypes of Ameloblastoma.

Uma Mudaliar, Avinash Tamgadge, Sandhya Tamgadge, Treville Pereira, Snehal Dhouskar, Sonali Rajhans, Gourav Salunke

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microscopy and ultrastructure. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Molecular biological findings of ameloblastoma.The Japanese dental science review · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Uma MudaliarDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Avinash TamgadgeDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Sandhya TamgadgeDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Treville PereiraDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Snehal DhouskarDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Sonali RajhansDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Gourav SalunkeDepartment of Oral and Maxillofacial Pathology and Microbiology, D Y Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
D.Y. Patil University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAmeloblastoma is a rare odontogenic neoplasm with high recurrence rates if improperly treated. If left untreated (or is treated inadequately), it can cause substantial morbidity, disfigurement, and even death. Hence, there is a need to explore the stromal cells too, which might play an important role in assessing its aggressive behavior and may help to predict the recurrence of different clinical variants of ameloblastoma. Myofibroblasts (MFs) are such cells which have been studied in various lesions. MATERIALS AND

methodsThis retrospective study involved archival tissues of ameloblastoma. Among a total of 40 cases, 12 cases of SMA (solid multicystic ameloblastoma), 10 cases of unicystic ameloblastoma (UA), 8 cases of desmoplastic ameloblastoma, and 10 cases of oral squamous cell carcinoma were selected as control. Immunohistochemical staining with anti-alpha-smooth muscle actin antibody was done. Interpretation of ten examined fields was counted by three observers.

resultsSignificant difference in the number of MFs in SMA and UA and desmoplastic ameloblastoma and UA (

conclusionA significant correlation was obtained between the number of MF in all the three clinical variants, i.e., SMA, UA, and desmoplastic ameloblastoma (

Indexed as

Alpha-smooth muscle actinameloblastomaclinical variantstypes

Identifiers

PMID31548924
PMCPMC6753696
OpenAlexW2969850841

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.