Evidence map›Paper›PMID 31548868›Full record

ArticleBiotechnology for biofuels2019

Microbial biosynthesis of lactate esters.

Jong-Won Lee, Cong T Trinh

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. (Food chemistry: X · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Production of Esters inMicroorganisms · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Alcohol acyltransferases for the biosynthesis of esters.Biotechnology for biofuels and bioproducts · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Microbial production of advanced biofuels.Nature reviews. Microbiology · 2021
    Review
  19. Article
  20. Development of a Genome-Scale Metabolic Model ofFrontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jong-Won Lee1Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, TN USA.
Cong T Trinh1Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, TN USA.ORCID 0000-0002-8362-725X
Oak Ridge National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGreen organic solvents such as lactate esters have broad industrial applications and favorable environmental profiles. Thus, manufacturing and use of these biodegradable solvents from renewable feedstocks help benefit the environment. However, to date, the direct microbial biosynthesis of lactate esters from fermentable sugars has not yet been demonstrated.

resultsIn this study, we present a microbial conversion platform for direct biosynthesis of lactate esters from fermentable sugars. First, we designed a pyruvate-to-lactate ester module, consisting of a lactate dehydrogenase (

conclusionsWe have successfully established the biosynthesis pathway of lactate esters from fermentable sugars and demonstrated for the first time the direct fermentative production of lactate esters from glucose using an

Indexed as

Acetate esterAlcohol acyltransferaseEscherichia coliEsterEthyl lactateGreen solventIsobutyl lactateLactate esterModular cell

Identifiers

PMID31548868
PMCPMC6753613
OpenAlexW2974729151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.