Evidence map›Paper›PMID 31548719›Full record

ArticleNature genetics2019

Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'.

Mariano J Alvarez, Pengrong Yan, Mary L Alpaugh, Michaela Bowden, Ewa Sicinska, Chensheng W Zhou, Charles Karan, Ronald B Realubit, Prabhjot S Mundi, Adina Grunn and 11 more

Abstract readLetterComment
In one paragraph

Article in Nature genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Multifaceted modeling of small intestinal neuroendocrine tumors.Endocrine oncology (Bristol, England) · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Mariano J AlvarezDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA.
Pengrong YanChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-0021-6461
Mary L AlpaughChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-0008-2718
Michaela BowdenDepartment of Translational Medicine, Bristol-Meyers Squibb, Boston, MA, USA.
Ewa SicinskaDepartment of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA.
Chensheng W ZhouDepartment of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA.
Charles KaranDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4012-8677
Ronald B RealubitDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA.
Prabhjot S MundiDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA.
Adina GrunnDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA.
Dirk JägerMedical Oncology, National Center for Tumor Diseases Heidelberg, University Medical Center Heidelberg, Heidelberg, Germany.
John A ChabotDepartment of Surgery, Columbia University Irvin Medical Center, New York, NY, USA.
Antonio T FojoHerbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
Paul E ObersteinDepartment of Medical Oncology, Perlmutter Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-5918-6004
Hanina HibshooshHerbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
Jeffrey W MilsomColon and Rectal Surgery, Weill Cornell Medicine, New York, NY, USA.
Matthew H KulkeDepartment of Hematology and Medical Oncology, Boston University Cancer Center, Boston, MA, USA.
Massimo LodaDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Gabriela ChiosisChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Diane L Reidy-LagunesDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Andrea CalifanoDepartment of Systems Biology, Columbia University Irvin Medical Center, New York, NY, USA. califano@cumc.columbia.edu.ORCID http://orcid.org/0000-0003-4742-3679

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
Predicting Cancer Cell Response to Endogenous and Exogenous Perturbations at the Single Cell LevelR35CA197745 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANDREA CALIFANO · 2015 to 2026
$11.5M
Translating Stress Response Targeted Therapy for B-Cell LymphomasP50CA192937 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ZELENETZ, ANDREW D. · 2016 to 2020
$10.9M
Project 3: Structural Basis for grp94 Drug Development and Chaperone FunctionP01CA186866 · NCI · OHIO STATE UNIVERSITY · PI CHIOSIS, GABRIELA · 2015 to 2019
$6.7M
Systematic Identification and Pharmacological Targeting of Tumor Dependencies for Precision Cancer MedicineU01CA217858 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2017 to 2021
$6.1M
Biomarkers for predicting response to Hsp90 therapyR01CA172546 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CHIOSIS, GABRIELA, DUNPHY, MARK P. · 2013 to 2017
$2.9M
High-performance compute cluster for biomedical computingS10OD012351 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2012 to 2012
$2.0M
A chemical chaperomics platform for ADR56AG061869 · NIA · SLOAN-KETTERING INST CAN RESEARCH · PI CHIOSIS, GABRIELA · 2018 to 2019
$1.8M
Storage System for High Performance ComputingS10OD021764 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2016 to 2016
$600k
Biomarkers of response to Hsp90 inhibitors in triple-negative breast cancerR21CA158609 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CHIOSIS, GABRIELA · 2012 to 2013
$426k
NCI NIH HHS P01 CA186866NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA013696NCI NIH HHS P50 CA192937NCI NIH HHS R01 CA172546NCI NIH HHS R21 CA158609NCI NIH HHS R35 CA197745NCI NIH HHS U01 CA217858NIA NIH HHS R56 AG061869NIH HHS S10 OD012351NIH HHS S10 OD021764
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neuroendocrine TumorsPrecision MedicineCell LineHumansMedical Oncology

Identifiers

PMID31548719
PMCPMC7256901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.