Evidence map›Paper›PMID 31548693›Full record

ArticleNature chemical biology2019

Near-equilibrium glycolysis supports metabolic homeostasis and energy yield.

Junyoung O Park, Lukas B Tanner, Monica H Wei, Daven B Khana, Tyler B Jacobson, Zheyun Zhang, Sara A Rubin, Sophia Hsin-Jung Li, Meytal B Higgins, David M Stevenson and 2 more

Open access · greenAbstract read
In one paragraph

Article in Nature chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Article
  3. The return of metabolism: biochemistry and physiology of glycolysis.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  4. Inorganic phosphate and the rapid mobilization of metabolic energy in neurons.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
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  7. Article
  8. Article
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  12. Article
  13. HyperpolarizedMolecules (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Junyoung O ParkDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-9869-8993
Lukas B TannerLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Monica H WeiDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Daven B KhanaDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.ORCID http://orcid.org/0000-0002-8081-3436
Tyler B JacobsonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Zheyun ZhangLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Sara A RubinDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-3484-5461
Sophia Hsin-Jung LiDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.
Meytal B HigginsLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
David M StevensonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Daniel Amador-NoguezDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA. amadornoguez@wisc.edu.ORCID http://orcid.org/0000-0002-3568-3070
Joshua D RabinowitzLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. joshr@princeton.edu.ORCID http://orcid.org/0000-0002-1247-4727
Princeton University · USUniversity of Wisconsin–Madison · USUniversity of California, Los Angeles · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5M
NCI NIH HHS P30 CA072720
6 · The paper itself

Abstract

Glycolysis plays a central role in producing ATP and biomass. Its control principles, however, remain incompletely understood. Here, we develop a method that combines

Indexed as

GlycolysisAnimalsbcl-2-Associated X ProteinCell LineClostridium acetobutylicumEnergy MetabolismEscherichia coliGlucoseHomeostasisMiceNitrogenRuminiclostridium cellulolyticumBax protein, mousebcl-2-Associated X ProteinGlucoseNitrogen

Identifiers

PMID31548693
PMCPMC10184052
OpenAlexW2973960665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.