ArticleNature microbiology2019
Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 87 citations in OpenAlex.
- Effects of Supplemental Calcium and Vitamin D on Circulating Biomarkers of Gut Barrier Function in Patients with Colon Adenoma: A Randomized Clinical Trial.Cancer prevention research (Philadelphia, Pa.) · 2021Trial
- Burden and risk of elderly atopic dermatitis in Europe: A 2021 global burden of disease analysis.The World Allergy Organization journal · 2026Article
- Xenosialylation as immunological chimerism: a host-centered unifying model for viral and post-vaccination immune complications.European cytokine network · 2026Review
- The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.Journal of advanced research · 2026Review
- Bacterial exo-α-sialidases subvert the complement system through desialylation.bioRxiv : the preprint server for biology · 2026Article
- Discovery and characterization of vertebrate sialoglycan-binding proteins.Seminars in immunology · 2025Review
- Elevated muramyl dipeptide by sialic acid-facilitated postantibiotic pathobiont expansion contributes to gut dysbiosis-induced mastitis in mice.Journal of advanced research · 2025Article
- Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment.Scientific reports · 2025Article
- Article
- The physiological characteristics and applications of sialic acid.NPJ science of food · 2025Review
- Inverse-Vaccines for Rheumatoid Arthritis Re-establish Metabolic and Immunological Homeostasis in Joint Tissues.Advanced healthcare materials · 2025Article
- Temporal trends in disability adjusted life year and mortality for colorectal cancer attributable to a high red meat diet in China from 1990 to 2021: an analysis of the global burden of disease study 2021.BMC gastroenterology · 2024Article
- Segatella clades adopt distinct roles within a single individual's gut.NPJ biofilms and microbiomes · 2024Article
- Article
- Role of Xenosialylation in Post-Infectious and Post-Vaccination Complications, Including Covid-19 and Anti-SARS-CoV-2 Vaccination.Journal of inflammation research · 2024Article
- A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid 'xenoautoantigen' Neu5Gc in humans and the need for a standardised approach to quantification.Frontiers in molecular biosciences · 2024Review
- Insights into the Structure, Metabolism, Biological Functions and Molecular Mechanisms of Sialic Acid: A Review.Foods (Basel, Switzerland) · 2023Review
- Nutri-microbiome epidemiology, an emerging field to disentangle the interplay between nutrition and microbiome for human health.Protein & cell · 2023Review
- Biological Relevance of Goat Milk Oligosaccharides to Infant Health.Journal of agricultural and food chemistry · 2023Review
- Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors.PLoS pathogens · 2023Article
Corrections and comments
- Commented on by
Authors and funding
15 authors at 3 institutions in 2 countries.
Livia S Zaramela *Department of Pediatrics, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-1065-3799
Cameron Martino *Department of Pediatrics, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0001-9334-1258
Frederico Alisson-Silva *Department of Medicine and Cellular and Molecular Medicine, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0001-6717-2518
Steven D ReesSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-2258-7469
Sandra L DiazDepartment of Medicine and Cellular and Molecular Medicine, University of California, San Diego, CA, USA.
Léa ChuzelNew England Biolabs, Ipswich, MA, USA.
Mehul B GanatraNew England Biolabs, Ipswich, MA, USA.
Christopher H TaronNew England Biolabs, Ipswich, MA, USA.
Patrick SecrestDepartment of Medicine and Cellular and Molecular Medicine, University of California, San Diego, CA, USA.
Cristal ZuñigaDepartment of Pediatrics, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-0135-7429
Jianbo HuangSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA, USA.
Dionicio SiegelSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA, USA.
Geoffrey ChangSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA, USA.
Ajit VarkiDepartment of Medicine and Cellular and Molecular Medicine, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-2206-975X
Karsten ZenglerDepartment of Pediatrics, University of California, San Diego, CA, USA. kzengler@ucsd.edu.ORCID http://orcid.org/0000-0002-8062-3296
University of California San Diego · USNew England Biolabs (United States) · USUniversidade Federal do Rio de Janeiro · BR
Funding
BIOSYNTHESIS AND REGULATION OF SUBSTITUTED SIALIC ACIDSR01GM032373 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 1985 to 2022
$6.9MGRADUATE TRAINING PROGRAM IN BIONFORMATICST32GM008806 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAFNA, VINEET, REN, BING · 2001 to 2020
$6.2MTraining in Multi-Scale Analysis of Biological Structure and FunctionT32EB009380 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D. McCulloch, Padmini Rangamani · 2009 to 2026
$4.8MNIGMS NIH HHS R01 GM032373NIGMS NIH HHS T32 GM008806
Abstract
Dietary habits have been associated with alterations of the human gut resident microorganisms contributing to obesity, diabetes and cancer
Indexed as
DietGastrointestinal MicrobiomeAnimalsBacteriaBacteroidesCrystallography, X-RayEubacterialesFecesFemaleHumansMaleMetagenomicsMiceMice, Inbred C57BLNeuraminic AcidsNeuraminidaseNeuraminic AcidsNeuraminidaseN-glycolylneuraminic acidPolysaccharides
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.