ArticleJournal of exposure science & environmental epidemiology2020
Associations between sociodemographic characteristics and exposures to PBDEs, OH-PBDEs, PCBs, and PFASs in a diverse, overweight population of pregnant women.
Article in Journal of exposure science & environmental epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Associations between food insecurity in high-income countries and pregnancy outcomes: A systematic review and meta-analysis.PLoS medicine · 2024Pooled it
- Determinants of maternal and neonatal PFAS concentrations: a review.Environmental health : a global access science source · 2023Pooled it
- High-resolution metabolomics of maternal polybrominated diphenyl ethers (PBDE) exposure and preterm birth in the Atlanta African American Maternal-Child Cohort.Communications medicine · 2026Article
- Housing characteristics, dietary patterns, and sociodemographic characteristics as predictors of persistent organic pollutant exposure among African American pregnant women in Atlanta.Environmental research · 2025Article
- Associations between brominated flame retardants, including polybrominated diphenyl ethers, and immune responses among women in the California Teachers Study.Frontiers in epidemiology · 2025Article
- Endocrine disrupting chemical mixture exposure and risk of papillary thyroid cancer in U.S. military personnel: A nested case-control study.The Science of the total environment · 2024Article
- Hormonal Injustice: Environmental Toxicants as Drivers of Endocrine Health Disparities.Endocrinology and metabolism clinics of North America · 2023Review
- Bioinformatic analyses of hydroxylated polybrominated diphenyl ethers toxicities on impairment of adrenocortical secretory function.Environmental health and preventive medicine · 2022Article
- Environmental exposure during pregnancy and the risk of childhood allergic diseases.World journal of pediatrics : WJP · 2021Review
- Persistent organic pollutants and maternal glycemic outcomes in a diverse pregnancy cohort of overweight women.Environmental research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
Exposures to persistent organohalogen chemicals during pregnancy are associated with adverse health effects. Low-income, minority women with pre-existing co-morbidities may be particularly vulnerable to these exposures, but have historically been understudied. We aimed to characterize exposures to multiple chemical classes among a sample of ethnically diverse, lower income, overweight or obese pregnant women. Serum concentrations of polybrominated diphenyl ethers (PBDEs) and their hydroxylated metabolites (OH-PBDEs), polychlorinated biphenyls (PCBs), and poly- and perfluoroalkyl substances (PFASs) were measured in 98 pregnant women (California; 2011-2013). Aggregate exposures were evaluated using correlational clustering, a "chemical burden" score, and PCA. Associations between sociodemographic characteristics and individual and aggregate exposures were evaluated using multivariable linear regression. Clustering and PCA both produced four groupings: (PC1) PBDEs/OH-PBDEs, (PC2) PCBs, (PC3) PFNA/PFOA/PFDeA, (PC4) PFHxS/PFOS. Race/ethnicity and prepregnancy BMI were associated with PBDEs, OH-PBDEs and PC1. Maternal age was associated with PCBs and PC2. Parity was associated with PBDEs, OH-PBDEs and PC2. Poverty was negatively associated with PCBs, whereas food insecurity was positively associated with PFOS. We observed variations in sociodemographic profiles of exposures by chemical class and weak across-class correlations. These findings have implications for epidemiologic studies of chemical mixtures and for exposure reduction strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.