ArticleJournal of human hypertension2020
Arterial stiffness and 5-year mortality in patients with peripheral arterial disease.
Article in Journal of human hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Serum Osteoprotegerin Level Is Not a Localizing Biomarker of Atherosclerosis Affected by Kidney Function.Diagnostics (Basel, Switzerland) · 2026Article
- Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis.Diagnostics (Basel, Switzerland) · 2025Review
- Association between calf circumference and cardiovascular health indicators in patients with peripheral artery disease.Einstein (Sao Paulo, Brazil) · 2025Article
- Association of estimated pulse wave velocity with cognitive function in a multiethnic diverse population: The Northern Manhattan Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Focus on Prevention: Peripheral Arterial Disease and the Central Role of the Cardiologist.Journal of clinical medicine · 2023Review
- Benefits of combined exercise training on arterial stiffness and blood pressure in spontaneously hypertensive rats treated or not with dexamethasone.Frontiers in physiology · 2022Article
- NT-proBNP as a Potential Marker of Cardiovascular Damage in Children with Chronic Kidney Disease.Journal of clinical medicine · 2021Article
- Comparison between estimated and brachial-ankle pulse wave velocity for cardiovascular and overall mortality prediction.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among patients with peripheral arterial disease (PAD) the risk of mortality remains extremely high. We investigated whether arterial stiffness evaluated by aortic Pulse Wave Velocity (aPWV) and Augmentation index normalized for a standard heart rate of 75 bpm (Aix@75), predict cardiovascular disease (CVD) and total mortality in PAD and No-PAD patients. In 231 PAD patients (ankle-brachial index-ABI ≤ 0.9) and 167 No-PAD (ABI ≥ 0.91 < 1.3) the aPWV and Aix @75HR were evaluated using arterial tonometry and ABI values were obtained using an 8-MHz Doppler probe. The CVD and total mortality rates in relation to aPWV and Aix@75HR were analyzed using Cox regression model. During a mean follow-up of 5.4 ± 2 years 39 (16.9%) deaths occurred in PAD patients and 8 (4.8%) in No-PAD. In the population study, the age was a predictor of CVD mortality (HR = 0.143, 95% CI, 0.06-0.23; p = 0.0004) while the aPWV, was a predictor of total mortality (HR = 1.18, 95% CI, 1.07-1.30; p = 0.0008). In the PAD group, the aPWV remained associated with an increased risk for total mortality (HR = 1.14, 95% CI, 1.03-1.27; p = 0.010). An increase of aPWV may be an indicator of total mortality in PAD patients.
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