Evidence map›Paper›PMID 31548529›Full record

ArticleAntibodies (Basel, Switzerland)2017

Epitope Sequences in Dengue Virus NS1 Protein Identified by Monoclonal Antibodies.

Leticia Barboza Rocha, Rubens Prince Dos Santos Alves, Bruna Alves Caetano, Lennon Ramos Pereira, Thais Mitsunari, Jaime Henrique Amorim, Juliana Moutinho Polatto, Viviane Fongaro Botosso, Neuza Maria Frazatti Gallina, Ricardo Palacios and 7 more

Open access · goldAbstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  6. Anti-DENV-NS1 monoclonal antibody for the differential histopathological diagnosis of hemorrhagic fever caused by dengue.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  7. Review
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  14. Special Issue: Monoclonal Antibodies.Antibodies (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Leticia Barboza RochaLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. leticia.rocha@butantan.gov.br.
Rubens Prince Dos Santos AlvesLaboratório de Desenvolvimento de Vacinas, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. rubens.bmc@gmail.com.
Bruna Alves CaetanoLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. bruna.caetano@butantan.gov.br.
Lennon Ramos PereiraLaboratório de Desenvolvimento de Vacinas, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. lennon_rp@usp.br.
Thais MitsunariLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. thais.mitsunari@butantan.gov.br.
Jaime Henrique AmorimLaboratório de Desenvolvimento de Vacinas, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. jh.biomedico@gmail.com.
Juliana Moutinho PolattoLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. juliana.yassuda@butantan.gov.br.
Viviane Fongaro BotossoLaboratório de Virologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. viviane.botosso@butantan.gov.br.
Neuza Maria Frazatti GallinaDivisão de Desenvolvimento Tecnológico e Produção; Instituto Butantan, São Paulo, 05503-900, SP, Brazil. neuza.gallina@butantan.gov.br.
Ricardo PalaciosDivisão de Ensaios Clínicos e Farmacovigilância, Instituto Butantan, São Paulo, 05503-900, SP, Brazil. ricardo.palacios@butantan.gov.br.
Alexander Roberto PreciosoDivisão de Ensaios Clínicos e Farmacovigilância, Instituto Butantan, São Paulo, 05503-900, SP, Brazil. alexander.precioso@butantan.gov.br.
Celso Francisco Hernandes GranatoDepartamento de Medicina, Disciplina de Doenças Infecciosas e Parasitárias, Universidade Federal de São Paulo, São Paulo, 04023-062, SP, Brazil. celso.granato@grupofleury.com.br.
Danielle Bruna Leal OliveiraLaboratório de Virologia Molecular e Clínica, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. danibruna@gmail.com.
Vanessa Barbosa da SilveiraLaboratório de Virologia Molecular e Clínica, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. vanessa.silveirabio@gmail.com.
Daniela LuzLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. daniedaluz@yahoo.com.br.
Luís Carlos de Souza FerreiraLaboratório de Desenvolvimento de Vacinas, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, 05508-000, SP, Brazil. lcsf@usp.br.
Roxane Maria Fontes PiazzaLaboratório de Bacteriologia, Instituto Butantan, São Paulo, 05503-900 SP, Brazil. roxane@butantan.gov.br.ORCID 0000-0003-0068-8506
Instituto Butantan · BRUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2009/53894-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2011/51761-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/09096-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/06589-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/50955-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/17595-0
6 · The paper itself

Abstract

Dengue nonstructural protein 1 (NS1) is a multi-functional glycoprotein with essential functions both in viral replication and modulation of host innate immune responses. NS1 has been established as a good surrogate marker for infection. In the present study, we generated four anti-NS1 monoclonal antibodies against recombinant NS1 protein from dengue virus serotype 2 (DENV2), which were used to map three NS1 epitopes. The sequence

Indexed as

amino acid sequencesantibody recognitiondengue virusmAbsNS1Zika virus

Identifiers

PMID31548529
PMCPMC6698852
OpenAlexW2762381237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.