Evidence map›Paper›PMID 31548437›Full record

ArticleJournal of epidemiology2020

Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017.

Li-Ping Xie, Wei-Li Yan, Min Huang, Mei-Rong Huang, Sun Chen, Guo-Ying Huang, Fang Liu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06641817 (An Observed Research), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06641817 enrolling by invitationnot on this mapstarted 2023, after this paper: background citation

An Observed Research: to Assess Kawasaki Disease with Cardiovascular Imaging

TypeobservationalSponsorWest China Second University HospitalRan2023 to 2033Enrolled500ConditionsKawasaki Disease
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Randomized trial of different initial intravenous immunoglobulin regimens in Kawasaki disease.Pediatrics international : official journal of the Japan Pediatric Society · 2021
    Trial
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  13. Short-term exposure to CO and NOFrontiers in public health · 2026
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  18. Diagnostic Value ofPediatric cardiology · 2025
    Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Li-Ping XieHeart Center, Children's Hospital of Fudan University.ORCID http://orcid.org/0000-0001-7657-9707
Wei-Li YanDepartment of Clinical Epidemiology, Children's Hospital of Fudan University.
Min HuangDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University.
Mei-Rong HuangPediatric Heart Center, Shanghai Children's Medical Center.
Sun ChenDepartment of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine.
Guo-Ying HuangHeart Center, Children's Hospital of Fudan University.
Fang LiuHeart Center, Children's Hospital of Fudan University.ORCID http://orcid.org/0000-0003-4841-8206
Children's Hospital of Fudan University · CNShanghai Children's Medical Center · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe sought to investigate epidemiologic features of Kawasaki disease (KD) in Shanghai from 2013 through 2017 and identify risk factors for coronary artery lesions (CAL).

methodsAs in our previous three surveys, a set of questionnaires and diagnostic guidelines for KD were sent to 50 hospitals providing pediatric medical care in Shanghai. Medical records of KD patients diagnosed from January 2013 through December 2017 were retrospectively analyzed. Multivariate logistic regression analysis was performed to identify risk factors for CAL.

resultsA total of 4,452 cases were enrolled. Male-to-female ratio was 1.7:1. The incidence of KD was 68.8 to 107.3 per 100,000 children aged <5 years from 2013 to 2017. Age at onset ranged from 15 days to 14.0 years (median: 1.8 years). KD occurred more frequently in spring and summer. Of 4,325 patients (97.0%) receiving intravenous immunoglobulin (IVIG), 362 (8.4%) were resistant to initial IVIG. CAL occurred in 406 (9.1%) patients, including 118 (2.7%) with medium aneurysms and 31 (0.7%) with giant aneurysms. Recurrent cases were 60 (1.3%). No death was found in this survey. Higher platelet levels, lower albumin levels, male sex, incomplete KD, IVIG resistance, and receiving initial IVIG ≤4 days or >10 days, were independently associated with CAL.

conclusionsThe incidence of KD in Shanghai had substantially increased while the proportion of CAL had substantially decreased as compared with our previous surveys. Higher platelet levels, lower albumin levels, male sex, incomplete KD, IVIG resistance, and receiving initial IVIG ≤4 days or >10 days, were risk factors for CAL.

Indexed as

AdolescentAge of OnsetChildChild, PreschoolChinaCoronary Artery DiseaseFemaleHumansImmunoglobulins, IntravenousIncidenceInfantMaleMucocutaneous Lymph Node SyndromeRetrospective StudiesRisk FactorsSurveys and QuestionnairesImmunoglobulins, Intravenouscoronary artery lesionepidemiologyKawasaki diseaseShanghai

Identifiers

PMID31548437
PMCPMC7492704
OpenAlexW2973465475

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.