ArticleProceedings of the National Academy of Sciences of the United States of America2019
Parkinson's disease-associated
Open access · bronzeAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 95 citations in OpenAlex.
- Inter-Organelle Membrane Contact Sites as Physiological Regulatory Hubs in the Brain: From Neurons to Glial Cells.Biomolecules · 2026Review
- Lipid Metabolism in Central Nervous System Diseases: Pathological Mechanisms and Therapeutic Advances.CNS neuroscience & therapeutics · 2026Review
- Therapeutic Advances in Major NBIA Disorders: Current Strategies and Translational Challenges.Neurology international · 2026Review
- Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments.Movement disorders clinical practice · 2026Review
- Liver-Specific Suppression of PLA2G6/iPLAFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Parkinson's disease-associated PLA2G6 protects IP3R1 protein to control ER-mitochondria tethering and CaNature communications · 2026Article
- Metabolic profiles associated with fat loss in Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2026Article
- Loss of mouse C19orf12 homolog disturbs tubular ER homeostasis and leads to neuroaxonal dystrophy.Acta neuropathologica communications · 2025Article
- Decanoic acid extends lifespan and modulates metabolism in models of PLA2G6-associated neurodegeneration.Disease models & mechanisms · 2025Article
- Parkinson disease is a fatty acidopathy.Nature reviews. Neurology · 2025Review
- An Update and Perspectives on Mitochondrial Membrane Protein-Associated Neurodegeneration andBrain sciences · 2025Review
- Natural variation in phospholipase IPLA2-VIA contributes to starvation sensitivity inbioRxiv : the preprint server for biology · 2025Article
- The Role of Cardiolipin in Brain Bioenergetics, Neuroinflammation, and Neurodegeneration.Molecular neurobiology · 2025Review
- The role of dopaminergic medication and specific pathway alterations in idiopathic andScience advances · 2025Article
- Lipid metabolism, remodelling and intercellular transfer in the CNS.Nature reviews. Neuroscience · 2025Review
- Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young-Onset PLA2G6 Parkinson's Disease iPSCs.Journal of neurochemistry · 2025Article
- GABAergic neurons are a key cell type in aFrontiers in neuroscience · 2025Article
- Link between Parkinson's disease and melanoma: insights into the influence of theFrontiers in oncology · 2025Review
- A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism.Cell reports. Medicine · 2024Article
- Role of Lipids in the Pathogenesis of Parkinson's Disease.International journal of molecular sciences · 2024Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 4 institutions in 1 country.
Akio MoriDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Taku HatanoDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.ORCID 0000-0002-6808-0444
Tsuyoshi InoshitaDepartment of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Kahori Shiba-FukushimaDepartment of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Takahiro KoinumaDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Hongrui MengResearch Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Shin-Ichiro KuboDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Spencer SprattDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Changxu CuiDepartment of Research for Parkinson's Disease, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Chikara YamashitaDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Yoshimi MikiCenter for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033 Tokyo, Japan.ORCID 0000-0002-8587-0333
Kei YamamotoDivision of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 770-8513 Tokushima, Japan.
Tetsuya HirabayashiLaboratory of Biomembrane, Tokyo Metropolitan Institute of Medical Science, 156-8506 Tokyo, Japan.ORCID 0000-0001-8099-5367
Makoto MurakamiCenter for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 113-0033 Tokyo, Japan.
Yoshikazu TakahashiJapan Agency for Medical Research and Development-Core Research for Evolutionary Medical Science and Technology (AMED-CREST), AMED, 100-0004 Tokyo, Japan.
Hideo ShindouJapan Agency for Medical Research and Development-Core Research for Evolutionary Medical Science and Technology (AMED-CREST), AMED, 100-0004 Tokyo, Japan.
Takashi NonakaDementia Research Project, Tokyo Metropolitan Institute of Medical Science, 156-8506 Tokyo, Japan.ORCID 0000-0002-0830-9403
Masato HasegawaDementia Research Project, Tokyo Metropolitan Institute of Medical Science, 156-8506 Tokyo, Japan.
Ayami OkuzumiDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Yuzuru ImaiDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan; yzimai@juntendo.ac.jp nhattori@juntendo.ac.jp.ORCID 0000-0003-2924-5231
Nobutaka HattoriDepartment of Neurology, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan; yzimai@juntendo.ac.jp nhattori@juntendo.ac.jp.
Juntendo University · JPJapan Agency for Medical Research and Development · JPTokyo Metropolitan Institute of Medical Science · JPThe University of Tokyo · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations in the
Indexed as
alpha-SynucleinAnimalsAnimals, Genetically ModifiedBrainCell MembraneDopaminergic NeuronsDrosophila melanogasterDrosophila ProteinsEndoplasmic Reticulum StressFemaleGroup VI Phospholipases A2Group X Phospholipases A2HumansMaleMitochondriaMitochondrial Proteinsalpha-SynucleinC19orf12 protein, humanDrosophila ProteinsGroup VI Phospholipases A2Group X Phospholipases A2iPLA2-VIA protein, DrosophilaMitochondrial ProteinsPhospholipidsPLA2G6 protein, humanDrosophilaER stresslipidsParkinson’s diseaseα-synuclein
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.