Evidence map›Paper›PMID 31548396›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder.

David Pagliaccio, Rachel Middleton, Dianne Hezel, Shari Steinman, Ivar Snorrason, Marina Gershkovich, Raphael Campeas, Anthony Pinto, Page Van Meter, H Blair Simpson and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07278206 (Mitigating Cognitive Problems and Fatigue With Brain Stimulation in Long COVID), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07278206 narecruitingnot on this mapstarted 2025, after this paper: background citation

Mitigating Cognitive Problems and Fatigue With Brain Stimulation in Long COVID

TypeinterventionalSponsorAmsterdam UMC, location VUmcRan2025 to 2029Enrolled66ConditionsLong COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)ArmsRepetitive Transcranial Magnetic Stimulation, Sham device
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  13. Network-based functional connectivity predicts response to exposure therapy in unmedicated adults with obsessive-compulsive disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  14. Review
  15. Functional Brain Imaging and OCD.Current topics in behavioral neurosciences · 2021
    Review
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

David PagliaccioDivision of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY 10032; david.pagliaccio@nyspi.columbia.edu.ORCID 0000-0002-1214-1965
Rachel MiddletonCenter for OCD and Related Disorders, New York State Psychiatric Institute, New York, NY 10032.
Dianne HezelCenter for OCD and Related Disorders, New York State Psychiatric Institute, New York, NY 10032.
Shari SteinmanCenter for OCD and Related Disorders, New York State Psychiatric Institute, New York, NY 10032.
Ivar SnorrasonCenter for OCD and Related Disorders, New York State Psychiatric Institute, New York, NY 10032.
Marina GershkovichDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Raphael CampeasDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Anthony PintoDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Page Van MeterCenter for OCD and Related Disorders, New York State Psychiatric Institute, New York, NY 10032.
H Blair SimpsonDivision of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY 10032.
Rachel MarshDivision of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY 10032.
New York State Psychiatric InstituteNew York Psychoanalytic Society and Institute · USDonald & Barbara Zucker School of Medicine at Hofstra/Northwell · US

Funding

Control and Reward Circuits as Targets for Repetitive Thoughts and BehaviorsR01MH104648 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MARSH, RACHEL, SIMPSON, HELEN BLAIR · 2014 to 2017
$2.8M
NIMH NIH HHS R01 MH104648
6 · The paper itself

Abstract

Exposure and ritual prevention (EX/RP) is an effective first-line treatment for obsessive-compulsive disorder (OCD), but only some patients achieve minimal symptoms following EX/RP. Herein, we investigate whether task-based neural activity can predict who responds best to EX/RP. Unmedicated adult patients with OCD (

Indexed as

Implosive TherapyMagnetic Resonance ImagingAdultCase-Control StudiesFemaleHumansMaleObsessive-Compulsive DisorderYoung AdultconflictexposurefMRIOCDpsychotherapy

Identifiers

PMID31548396
PMCPMC6789627
OpenAlexW2975889270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.