ArticleProceedings of the National Academy of Sciences of the United States of America2019
A marine plasmid hitchhiking vast phylogenetic and geographic distances.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Article
- Genomic and functional characterization of Pseudosulfitobacter pseudonitzschiae BPC-C4-2: a growth-promoting symbiont in Antarctic Ulva communities.BMC genomics · 2026Article
- Article
- Fluid flow generates bacterial conjugation hot spots by increasing the rate of shear-driven cell-cell encounters.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Microbial functional diversity and redundancy: moving forward.FEMS microbiology reviews · 2025Review
- Plasmid-Borne Biosynthetic Gene Clusters within a Permanently Stratified Marine Water Column.Microorganisms · 2024Article
- Structure and dispersion of the conjugative mobilome in surface ocean bacterioplankton.ISME communications · 2024Article
- Global transmission of broad-host-range plasmids derived from the human gut microbiome.Nucleic acids research · 2023Article
- Characterization of the Environmental Plasmidome of the Red Sea.Microbiology spectrum · 2023Article
- Mutation-induced infections of phage-plasmids.Nature communications · 2023Article
- Beyond the ABCs-Discovery of Three New Plasmid Types inMicroorganisms · 2022Article
- Fatal affairs - conjugational transfer of a dinoflagellate-killing plasmid between marineMicrobial genomics · 2022Article
- Segregational Drift Constrains the Evolutionary Rate of Prokaryotic Plasmids.Molecular biology and evolution · 2021Article
- Comparison of Alginate Utilization Pathways in Culturable Bacteria Isolated From Arctic and Antarctic Marine Environments.Frontiers in microbiology · 2021Article
- Biosolids as a Source of Antibiotic Resistance Plasmids for Commensal and Pathogenic Bacteria.Frontiers in microbiology · 2021Article
- Quantifying the transmission of antimicrobial resistance at the human and livestock interface with genomics.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Review
- Synthetic Biology for Terraformation Lessons from Mars, Earth, and the Microbiome.Life (Basel, Switzerland) · 2020Article
- Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Horizontal gene transfer (HGT) plays an important role in bacterial evolution and serves as a driving force for bacterial diversity and versatility. HGT events often involve mobile genetic elements like plasmids, which can promote their own dissemination by associating with adaptive traits in the gene pool of the so-called mobilome. Novel traits that evolve through HGT can therefore lead to the exploitation of new ecological niches, prompting an adaptive radiation of bacterial species. In this study, we present phylogenetic, biogeographic, and functional analyses of a previously unrecognized RepL-type plasmid found in diverse members of the marine Roseobacter group across the globe. Noteworthy, 100% identical plasmids were detected in phylogenetically and geographically distant bacteria, revealing a so-far overlooked, but environmentally highly relevant vector for HGT. The genomic and functional characterization of this plasmid showed a completely conserved backbone dedicated to replication, stability, and mobilization as well as an interchangeable gene cassette with highly diverse, but recurring motifs. The majority of the latter appear to be involved in mechanisms coping with toxins and/or pollutants in the marine environment. Furthermore, we provide experimental evidence that the plasmid has the potential to be transmitted across bacterial orders, thereby increasing our understanding of evolution and microbial niche adaptation in the environment.
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