Evidence map›Paper›PMID 31548375›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Apparent thinning of human visual cortex during childhood is associated with myelination.

Vaidehi S Natu, Jesse Gomez, Michael Barnett, Brianna Jeska, Evgeniya Kirilina, Carsten Jaeger, Zonglei Zhen, Siobhan Cox, Kevin S Weiner, Nikolaus Weiskopf and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 206 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
206citing papers in PubMed, 5 pooled it
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

206 citing papers in PubMed, 5 syntheses or guidelines pooled it, 360 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Early psychosocial deprivation alters the refinement of neural dynamics across adolescence.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Trial
  7. Trial
  8. Trial
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Sulcal pleating captures functional boundaries in human visual cortex.bioRxiv : the preprint server for biology · 2026
    Article
  18. Review
  19. Article
  20. Article

146 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Vaidehi S NatuDepartment of Psychology, Stanford University, Stanford, CA 94305; vnatu@stanford.edu.
Jesse GomezNeurosciences Program, Stanford University School of Medicine, Stanford, CA 94305.
Michael BarnettDepartment of Psychology, University of Pennsylvania, Philadelphia, PA 19104.
Brianna JeskaDepartment of Psychology, Stanford University, Stanford, CA 94305.
Evgeniya KirilinaDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany.
Carsten JaegerDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany.
Zonglei ZhenDepartment of Psychology, Stanford University, Stanford, CA 94305.ORCID 0000-0002-6748-6434
Siobhan CoxDepartment of Psychology, Stanford University, Stanford, CA 94305.
Kevin S WeinerDepartment of Psychology, University of California, Berkeley, CA 94720.
Nikolaus WeiskopfDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany.
Kalanit Grill-SpectorDepartment of Psychology, Stanford University, Stanford, CA 94305.
Stanford University · USMax Planck Institute for Human Cognitive and Brain Sciences · DENeurological Surgery · USNeurosciences Institute · USUniversity of California, Berkeley · USUniversity of Pennsylvania · US

Funding

Development of Face Perception: Cross-sectional and Longitudinal InvestigationsR01EY022318 · NEI · STANFORD UNIVERSITY · PI GRILL-SPECTOR, KALANIT · 2012 to 2022
$5.2M
Functional-neuroanatomy of high-level visual cortex: a quantitative multimodal approachR01EY023915 · NEI · STANFORD UNIVERSITY · PI Kalanit Grill-Spector · 2014 to 2026
$4.6M
Vision Research Training ProgramT32EY020485 · NEI · STANFORD UNIVERSITY · PI BARRES, BEN A, LIAO, YAPING JOYCE · 2010 to 2014
$795k
Development of Macromolecular Tissue in Visual Cortex and its Role in Neural Function and BehaviorF31EY027201 · NEI · STANFORD UNIVERSITY · PI GOMEZ, JESSE LEE · 2016 to 2017
$72k
NEI NIH HHS F31 EY027201NEI NIH HHS R01 EY022318NEI NIH HHS R01 EY023915NEI NIH HHS T32 EY020485
6 · The paper itself

Abstract

Human cortex appears to thin during childhood development. However, the underlying microstructural mechanisms are unknown. Using functional magnetic resonance imaging (fMRI), quantitative MRI (qMRI), and diffusion MRI (dMRI) in children and adults, we tested what quantitative changes occur to gray and white matter in ventral temporal cortex (VTC) from childhood to adulthood, and how these changes relate to cortical thinning. T

Indexed as

AdultBrainChildChild, PreschoolFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMyelin SheathVisual CortexWhite MatterYoung Adultcortical thicknessdevelopmentdiffusion MRIlongitudinalquantitative MRI

Identifiers

PMID31548375
PMCPMC6789966
OpenAlexW2976878096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.