Evidence map›Paper›PMID 31548339›Full record

ArticleRNA (New York, N.Y.)2019

Thermodynamic examination of pH and magnesium effect on U6 RNA internal loop.

Allison A O'Connell, Jared A Hanson, Darryl C McCaskill, Ethan T Moore, Daniel C Lewis, Neena Grover

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. RNA therapeutics: current status and future directions.Signal transduction and targeted therapy · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Allison A O'ConnellDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.
Jared A HansonDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.ORCID 0000-0002-5534-6303
Darryl C McCaskillDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.
Ethan T MooreDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.
Daniel C LewisDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.
Neena GroverDepartment of Chemistry and Biochemistry, Colorado College, Colorado Springs, Colorado 80903, USA.ORCID 0000-0002-4185-9650
Colorado College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

U6 RNA contains a 1 × 2-nt internal loop that folds and unfold during spliceosomal assembly and activation. The 1 × 2 loop consists of a C

Indexed as

Hydrogen-Ion ConcentrationMagnesiumNucleic Acid ConformationThermodynamicsBase SequenceDNAHydrogen BondingModels, MolecularMolecular ConformationMolecular StructureProtonsRNA, Small NuclearDNAMagnesiumProtonsRNA, Small NuclearU6 small nuclear RNAinternal loopsmagnesium ion–RNA interactionsRNA 1 × 2 loopRNA thermodynamicssingle-nucleotide bulge loopspliceosomal RNA

Identifiers

PMID31548339
PMCPMC6859860
OpenAlexW2976193527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.