Evidence map›Paper›PMID 31548327›Full record

ArticleInfection and immunity2019

In Staphylococcus aureus, the Particulate State of the Cell Envelope Is Required for the Efficient Induction of Host Defense Responses.

ByungHyun Kim, TingTing Jiang, Jun-Hyun Bae, Hye Su Yun, Seong Han Jang, Jung Hyun Kim, Jae Deog Kim, Jin-Hoe Hur, Kensuke Shibata, Kenji Kurokawa and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. A promisingClinical and experimental vaccine research · 2025
    Review
  2. Review
  3. Article
  4. The Role of Macrophages inFrontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

ByungHyun Kim *Host Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
TingTing Jiang *Host Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Jun-Hyun BaeHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Hye Su YunHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Seong Han JangHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Jung Hyun KimHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Jae Deog KimHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Jin-Hoe HurUNIST-Olympus Biomed Imaging Center, UNIST, Ulsan, Republic of Korea.
Kensuke ShibataDepartment of Microbiology and Immunology, Yamaguchi University, Graduate School of Medicine, Yamaguchi, Japan.
Kenji KurokawaFaculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan.
Yunjin JungHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Andreas PeschelInterfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-3209-8626
Taeok BaeDepartment of Microbiology and Immunology, Indiana University School of Medicine-Northwest, Gary, Indiana, USA.ORCID 0000-0002-0576-2851
Bok Luel LeeHost Defense Protein Laboratory, College of Pharmacy, Pusan National University, Busan, Republic of Korea brlee@pusan.ac.kr.
Pusan National University · KRIndiana University Northwest · USNagasaki International University · JPUlsan National Institute of Science and Technology · KRUniversity of Tübingen · DEYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon microbial infection, host immune cells recognize bacterial cell envelope components through cognate receptors. Although bacterial cell envelope components function as innate immune molecules, the role of the physical state of the bacterial cell envelope (i.e., particulate versus soluble) in host immune activation has not been clearly defined. Here, using two different forms of the staphylococcal cell envelope of

Indexed as

AnimalsCell WallChemokine CCL2Chemokine CXCL1FemaleImmunity, InnateLeukocyte L1 Antigen ComplexMacrophagesMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMonocytesNeutrophilsPhagocytosisCcl2 protein, mouseChemokine CCL2Chemokine CXCL1Cxcl1 protein, mouseLeukocyte L1 Antigen Complexcell envelopechemokineshost defenseinnate immunityphagocytesStaphylococcus aureus

Identifiers

PMID31548327
PMCPMC6867855
OpenAlexW2974873175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.