Evidence map›Paper›PMID 31548254›Full record

ArticleThe Plant cell2019

ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas.

Olivia Costantina Demurtas, Rita de Brito Francisco, Gianfranco Diretto, Paola Ferrante, Sarah Frusciante, Marco Pietrella, Giuseppe Aprea, Lorenzo Borghi, Mistianne Feeney, Lorenzo Frigerio and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 84 citations in OpenAlex.

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  4. Epigenomics Nutritional Insights ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Olivia Costantina DemurtasENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0003-3344-5754
Rita de Brito FranciscoDepartment of Plant and Microbial Biology, University of Zurich, 8008 Zurich, Switzerland.ORCID 0000-0001-7728-8477
Gianfranco DirettoENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0002-1441-0233
Paola FerranteENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0003-3071-2212
Sarah FruscianteENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0001-8161-3797
Marco PietrellaENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0002-8789-6860
Giuseppe ApreaENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy.ORCID 0000-0003-4969-2696
Lorenzo BorghiDepartment of Plant and Microbial Biology, University of Zurich, 8008 Zurich, Switzerland.ORCID 0000-0002-9631-9694
Mistianne FeeneySchool of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.ORCID 0000-0002-0057-7753
Lorenzo FrigerioSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.ORCID 0000-0003-4100-6022
Adriana CoricelloDepartment of Health Sciences, Magna Græcia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-3306-9261
Giosuè CostaDepartment of Health Sciences, Magna Græcia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-0947-9479
Stefano AlcaroDepartment of Health Sciences, Magna Græcia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-0437-358X
Enrico MartinoiaDepartment of Plant and Microbial Biology, University of Zurich, 8008 Zurich, Switzerland giovanni.giuliano@enea.it enrico.martinoia@botinst.uzh.ch.ORCID 0000-0001-8943-7089
Giovanni GiulianoENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, 00123, Rome, Italy giovanni.giuliano@enea.it enrico.martinoia@botinst.uzh.ch.ORCID 0000-0002-2486-0510
National Agency for New Technologies, Energy and Sustainable Economic Development · ITUniversity of Zurich · CHUniversity of Warwick · GBNational Agency for New Technologies Energy and Sustainable Economic Development · GBVNU Central Institute for Natural Resources and Environmental Studies · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compartmentation is a key strategy enacted by plants for the storage of specialized metabolites. The saffron spice owes its red color to crocins, a complex mixture of apocarotenoid glycosides that accumulate in intracellular vacuoles and reach up to 10% of the spice dry weight. We developed a general approach, based on coexpression analysis, heterologous expression in yeast (

Indexed as

ATP-Binding Cassette TransportersBiosynthetic PathwaysCarotenoidsCloning, MolecularCrocusFlowersGene Expression Regulation, PlantKineticsNicotianaPlant ExtractsPlant LeavesPlant ProteinsSaccharomyces cerevisiaeTissue DistributionVacuolesATP-Binding Cassette TransportersCarotenoidscrocinPlant ExtractsPlant Proteins

Identifiers

PMID31548254
PMCPMC6881118
OpenAlexW2975461972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.