Evidence map›Paper›PMID 31548243›Full record

ArticleDiabetes care2019

Visit-to-Visit Fasting Glucose Variability in Young Adulthood and Hippocampal Integrity and Volume at Midlife.

Zhenyu Xiong, Jiaying Li, Xiangbin Zhong, Shaozhao Zhang, Xiuting Sun, Huimin Zhou, Yunzhi Chen, Xiaodong Zhuang, Xinxue Liao

Abstract readEvaluation Study
In one paragraph

Article in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhenyu XiongThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jiaying LiNanfang Hospital of Southern Medical University, Guangzhou, China.
Xiangbin ZhongThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shaozhao ZhangThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiuting SunThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huimin ZhouThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yunzhi ChenThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiaodong ZhuangThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China zhuangxd3@mail.sysu.edu.cn.
Xinxue LiaoThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China liaoxinx@mail.sysu.edu.cn.ORCID 0000-0001-7631-1866

Funding

NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029C
6 · The paper itself

Abstract

objectiveTo determine whether visit-to-visit fasting glucose (VVFG) variability in young adulthood is associated with midlife hippocampal integrity and volume. RESEARCH DESIGN AND

methodsMultivariable-adjusted linear regression models were used to estimate the association between VVFG variability and brain MRI variables in 543 CARDIA study participants. VVFG variability was defined by the SD of FG (SD

resultsAfter multivariable adjustment, higher FG variability (1-SD increase) was associated with lower hippocampal FA (SD

conclusionsHigher VVFG variability in young adulthood is associated with lower midlife hippocampal integrity and volume, suggesting its value in predicting risk for hippocampal structural damage.

Indexed as

AdolescentAdultAgingBlood GlucoseClinical Trials as TopicFastingFemaleHippocampusHumansLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeRisk FactorsYoung AdultBlood Glucose

Identifiers

PMID31548243
PMCPMC7364671

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.