Evidence map›Paper›PMID 31548178›Full record

ArticleBiology open2019

Restriction of mitochondrial calcium overload by

Smijin K Soman, Michal Bazała, Marcus Keatinge, Oliver Bandmann, Jacek Kuznicki

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 57 citations in OpenAlex.

  1. Mitochondrial CaAntioxidants (Basel, Switzerland) · 2026
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  17. Mitochondrial calcium cycling in neuronal function and neurodegeneration.Frontiers in cell and developmental biology · 2023
    Review
  18. Article
  19. Acta biochimica et biophysica Sinica · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Smijin K SomanLaboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Księcia Trojdena 4, 02-109, Warsaw, Poland jacek.kuznicki@iimcb.gov.pl skarthullysoman@med.unr.edu.ORCID http://orcid.org/0000-0002-3891-118X
Michal BazałaLaboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Księcia Trojdena 4, 02-109, Warsaw, Poland.ORCID http://orcid.org/0000-0002-2237-2206
Marcus KeatingeMedical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK.ORCID http://orcid.org/0000-0003-2055-1187
Oliver BandmannMedical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK.
Jacek KuznickiLaboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Księcia Trojdena 4, 02-109, Warsaw, Poland jacek.kuznicki@iimcb.gov.pl skarthullysoman@med.unr.edu.ORCID http://orcid.org/0000-0001-6486-0657
International Institute of Molecular and Cell Biology · PLMedical Research Council · GB

Funding

Medical Research Council MR/R011354/1
6 · The paper itself

Abstract

The loss of dopaminergic neurons (DA) is a pathological hallmark of sporadic and familial forms of Parkinson's disease (PD). We have previously shown that inhibiting mitochondrial calcium uniporter (

Indexed as

CRISPR/Cas9mcuMitochondriaNeuroprotectionParkinson's diseaseZebrafish

Identifiers

PMID31548178
PMCPMC6826286
OpenAlexW2975840693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.