Evidence map›Paper›PMID 31548024›Full record

ArticleSeminars in pediatric neurology2019

Alterations in the Structural and Functional Connectivity of the Visuomotor Network of Children With Periventricular Leukomalacia.

Corinna M Bauer, Christos Papadelis

Abstract read
In one paragraph

Article in Seminars in pediatric neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Corinna M BauerDepartment of Ophthalmology, Massachusetts Eye and Ear, Laboratory for Visual Neuroplasticity, Harvard Medical School, Boston, MA. Electronic address: Corinna_Bauer@meei.harvard.edu.
Christos PapadelisDivision of Newborn Medicine, Boston Children's Hospital, Laboratory of Children's Brain Dynamics, Harvard Medical School, Boston, MA.

Funding

Multi-modal neuroimaging in children with congenital hemiplegia to assess functional and anatomical reorganization in relation to hand functionR21HD090549 · NICHD · COOK CHILDREN'S MEDICAL CENTER · PI PAPADELIS, CHRISTOS · 2017 to 2019
$446k
NICHD NIH HHS R21 HD090549
6 · The paper itself

Abstract

Children born preterm with periventricular leukomalacia (PVL) demonstrate increased difficulties with tasks requiring visuomotor integration. The visuomotor integration network encompasses brain regions within frontal, parietal, and occipital cortices. Because of their proximity to the lateral ventricle the underlying white matter pathways are at a high risk of damage following PVL-related hypoxic-ischemic white matter injury. This study provides an exploratory analysis of the structural and functional connections within the visuomotor integration network, along with an a priori evaluation of the superior longitudinal fasciculus, inferior fronto-occipital fasciculus, and frontal aslant tract. For each pathway, tracts within both hemispheres revealed decreased volume and number of reconstructed fibers and an increase in quantitative anisotropy and generalized fractional anisotropy. The connectivity results also indicate that there may be changes to both the structural integrity and functional integration of neural networks involved with visuomotor integration functions in children with PVL.

Indexed as

AdolescentAnisotropyBrain InjuriesBrain MappingFemaleHumansLeukomalacia, PeriventricularMaleNerve NetNeural PathwaysWhite MatterYoung Adult

Identifiers

PMID31548024
PMCPMC6761984

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.