Evidence map›Paper›PMID 31547569›Full record

ReviewInternational journal of molecular sciences2019

Soy Lecithin-Derived Liposomal Delivery Systems: Surface Modification and Current Applications.

Ngoc Thuy Trang Le, Van Du Cao, Thi Nhu Quynh Nguyen, Thi Thu Hong Le, Thach Thao Tran, Thai Thanh Hoang Thi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 159 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ngoc Thuy Trang LeInstitute of Research and Development, Duy Tan University, Danang 550000, Vietnam. thuytranglengoc@gmail.com.ORCID 0000-0002-9540-802X
Van Du CaoFaculty of Pharmacy, Lac Hong University, Buu Long Ward, Bien Hoa City, Dong Nai Province 810000, Vietnam. caovandulhu@gmail.com.
Thi Nhu Quynh NguyenFaculty of Pharmacy, Lac Hong University, Buu Long Ward, Bien Hoa City, Dong Nai Province 810000, Vietnam. ds.nhuquynhnguyen@gmail.com.
Thi Thu Hong LeFaculty of Pharmacy, Lac Hong University, Buu Long Ward, Bien Hoa City, Dong Nai Province 810000, Vietnam. Hongle5792@gmail.com.
Thach Thao TranFaculty of Pharmacy, Lac Hong University, Buu Long Ward, Bien Hoa City, Dong Nai Province 810000, Vietnam. tranthachthao185@gmail.com.
Thai Thanh Hoang ThiBiomaterials and Nanotechnology Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City 700000, Vietnam. hoangthithaithanh@tdtu.edu.vn.ORCID 0000-0002-2245-9029
Lac Hong University · VNDuy Tan University · VNTon Duc Thang University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of natural phospholipids for nanostructured drug delivery systems has attracted much attention in the past decades. Lecithin that was derived from naturally occurring in soybeans (SL) has introduced some auspicious accomplishments to the drug carrying aspect, like effectual encapsulation, controlled release, and successful delivery of the curative factors to intracellular regions in which they procure these properties from their flexible physicochemical and biophysical properties, such as large aqueous center and biocompatible lipid, self-assembly, tunable properties, and high loading capacity. Despite the almost perfect properties as a drug carrier, liposome is known to be quite quickly eliminated from the body systems. The surface modification of liposomes has been investigated in many studies to overcome this drawback. In this review, we intensively discussed the surface-modified liposomes that enhancing the targeting, cellular uptake, and therapeutic response. Moreover, the recent applications of soy lecithin-derived liposome, focusing on cancer treatment, brain targeting, and vaccinology, are also summarized.

Indexed as

BrainNeoplasmsAnimalsAntineoplastic AgentsHumansLiposomesPhytohemagglutininsPlant LectinsSoybean ProteinsSurface PropertiesVaccinesAntineoplastic AgentsLiposomesPhytohemagglutininsPlant Lectinssoybean lectinSoybean ProteinsVaccinesdrug delivery systemliposomesoy lecithinsurface modification

Identifiers

PMID31547569
PMCPMC6801558
OpenAlexW2973509508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.