Evidence map›Paper›PMID 31547487›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Biocompatible and Biodegradable Magnesium Oxide Nanoparticles with In Vitro Photostable Near-Infrared Emission: Short-Term Fluorescent Markers.

Asma Khalid, Romina Norello, Amanda N Abraham, Jean-Philippe Tetienne, Timothy J Karle, Edward W C Lui, Kenong Xia, Phong A Tran, Andrea J O'Connor, Bruce G Mann and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
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  9. Article
  10. Prospective of biosynthesizedSaudi journal of biological sciences · 2021
    Article
  11. Magnetic and Highly Luminescent Heterostructures of GdNanomaterials (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Asma KhalidSchool of Physics, University of Melbourne, Parkville, VIC 3010, Australia. asma.khalid@rmit.edu.au.
Romina NorelloSchool of Physics, University of Melbourne, Parkville, VIC 3010, Australia. r.norello22@gmail.com.
Amanda N AbrahamSchool of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia. amanda.abraham@rmit.edu.au.ORCID 0000-0002-4778-1372
Jean-Philippe TetienneSchool of Physics, University of Melbourne, Parkville, VIC 3010, Australia. jptetienne@gmail.com.
Timothy J KarleSchool of Physics, University of Melbourne, Parkville, VIC 3010, Australia. tkarle@unimelb.edu.au.
Edward W C LuiDepartment of Mechanical Engineering, University of Melbourne, Parkville, VIC 3010, Australia. ewlui@unimelb.edu.au.
Kenong XiaDepartment of Mechanical Engineering, University of Melbourne, Parkville, VIC 3010, Australia. k.xia@unimelb.edu.au.ORCID 0000-0002-3469-435X
Phong A TranFaculty of Science and Engineering, Queensland University of Technology, Brisbane, QLD 4000, Australia. phong.tran@qut.edu.au.
Andrea J O'ConnorDepartment of Chemical and Biomolecular Engineering, Particulate Fluids Processing Centre, Melbourne, VIC 3010, Australia. a.oconnor@unimelb.edu.au.ORCID 0000-0001-6925-885X
Bruce G MannThe Department of Surgery, University of Melbourne, Parkville, VIC 3010, Australia. bruce.mann@mh.org.au.
Richard de BoerThe Breast Service, Victorian Comprehensive Cancer Centre, Parkville, VIC 3052, Australia. Richard.DeBoer@wh.org.au.
Yanling HeDepartment of Physics, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China. heyl3@mail.sustc.edu.cn.
Alan Man Ching NgDepartment of Physics, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China. ngamc@sustc.edu.cn.
Aleksandra B DjurisicDepartment of Physics, University of Hong Kong, Pokfulam Road, Hong Kong, China. dalek@hku.hk.
Ravi ShuklaSchool of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia. ravi.shukla@rmit.edu.au.
Snjezana Tomljenovic-HanicSchool of Physics, University of Melbourne, Parkville, VIC 3010, Australia. snjezana.thanic@unimelb.edu.au.
The University of Melbourne · AURMIT University · AUSouthern University of Science and Technology · CNQueensland University of Technology · AUUniversity of Hong Kong · HKVictorian Comprehensive Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging of biological matter by using fluorescent nanoparticles (NPs) is becoming a widespread method for in vitro imaging. However, currently there is no fluorescent NP that satisfies all necessary criteria for short-term in vivo imaging: biocompatibility, biodegradability, photostability, suitable wavelengths of absorbance and fluorescence that differ from tissue auto-fluorescence, and near infrared (NIR) emission. In this paper, we report on the photoluminescent properties of magnesium oxide (MgO) NPs that meet all these criteria. The optical defects, attributed to vanadium and chromium ion substitutional defects, emitting in the NIR, are observed at room temperature in NPs of commercial and in-house ball-milled MgO nanoparticles, respectively. As such, the NPs have been successfully integrated into cultured cells and photostable bright in vitro emission from NPs was recorded and analyzed. We expect that numerous biotechnological and medical applications will emerge as this nanomaterial satisfies all criteria for short-term in vivo imaging.

Indexed as

bioimagingbiomarkingcancer cellsconfocal microscopyfluorescence nanoparticlesmagnesium oxide

Identifiers

PMID31547487
PMCPMC6835516
OpenAlexW2973819195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.