Evidence map›Paper›PMID 31547468›Full record

ArticleBrain sciences2019

Different Representation Procedures Originated from Multivariate Temporal Pattern Analysis of the Behavioral Response to Pain in Wistar Rats Tested in a Hot-Plate under Morphine.

Maurizio Casarrubea, Stefania Aiello, Andrea Santangelo, Giuseppe Di Giovanni, Giuseppe Crescimanno

Abstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Sensory Deficits in Mice with Lateral Spinal Cord Hemisection Mimic the Brown-Séquard Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Spinal Glycine Receptor Alpha 3 Cells Communicate Sensations of Chemical Itch in Hairy Skin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maurizio CasarrubeaLaboratory of Behavioral Physiology, Department of Biomedicine Neuroscience and Advanced Diagnostics, Human Physiology Section "Giuseppe Pagano", University of Palermo, Palermo 90133, Italy. maurizio.casarrubea@unipa.it.ORCID 0000-0002-3278-6621
Stefania AielloLaboratory of Behavioral Physiology, Department of Biomedicine Neuroscience and Advanced Diagnostics, Human Physiology Section "Giuseppe Pagano", University of Palermo, Palermo 90133, Italy. stefania.aiello@unipa.it.
Andrea SantangeloLaboratory of Behavioral Physiology, Department of Biomedicine Neuroscience and Advanced Diagnostics, Human Physiology Section "Giuseppe Pagano", University of Palermo, Palermo 90133, Italy. a.santangelo@ymail.com.
Giuseppe Di GiovanniLaboratory of Neurophysiology, Department of Physiology and Biochemistry Faculty of Medicine and Surgery, University of Malta, Msida 2080, Malta. giuseppe.digiovanni@um.edu.mt.ORCID 0000-0003-2006-563X
Giuseppe CrescimannoLaboratory of Behavioral Physiology, Department of Biomedicine Neuroscience and Advanced Diagnostics, Human Physiology Section "Giuseppe Pagano", University of Palermo, Palermo 90133, Italy. giuseppe.crescimanno@unipa.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporal pattern analysis is an advanced multivariate technique able to investigate the structure of behavior by unveiling the existence of statistically significant constraints among the interval length separating events in sequence. If on the one hand, such an approach allows investigating the behavioral response to pain in its most intimate and inner features, on the other hand, due to the meaning of the studies on pain, it is of relevant importance that the results utilize intuitive and easily comprehensible ways of representation. The aim of this paper is to show various procedures useful to represent the results originating from the multivariate T-pattern analysis of the behavioral response to pain in Wistar rats tested in a hot-plate and IP injected morphine or saline as a control.

Indexed as

hot-platemorphinemultivariate analysespainT-patternT-pattern analysis

Identifiers

PMID31547468
PMCPMC6770233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.