ArticleJournal of clinical medicine2019
The Neutrophil/Lymphocyte Count Ratio Predicts Mortality in Severe Traumatic Brain Injury Patients.
Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic value of neutrophil-to-lymphocyte ratio in patients with traumatic brain injury: A systematic review.Frontiers in neurology · 2022Pooled it
- Investigating the Effect of High-Dose Vitamin D3 Administration on Inflammatory Biomarkers in Patients with Moderate to Severe Traumatic Brain Injury: A Randomized Clinical Trial.Iranian journal of medical sciences · 2024Trial
- Humulus lupus extract rich in xanthohumol improves the clinical course in critically ill COVID-19 patients.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023Trial
- The role of NSE/GCS ratio on the seventh day as an independent predictor of 90-day outcomes in patients with severe traumatic brain injury.Journal of medical biochemistry · 2026Article
- Performance and accuracy of blood glucose and neutrophil-lymphocyte ratio as predictors of mortality in children and adolescents with traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Investigation of the Expression, Localization, and Acidosis-Associated Conformational Changes in Connexin 43 in Traumatic Brain Injury with the Development of a Neural Network Model for Assessing Systemic Inflammation.International journal of molecular sciences · 2025Article
- Article
- The Prognostic Value of Inflammatory Indexes in Patients With Severe Traumatic Brain Injury.Brain and behavior · 2025Article
- Outcome prediction in aneurysmal subarachnoid hemorrhage with world federation of neurological societies grade V (OPAS-V).Acta neurochirurgica · 2025Observational
- The association between neutrophil lymphocyte ratio and perihematomal edema in cerebral hemorrhage: a multicenter retrospective study.Frontiers in neurology · 2025Article
- Performance of the neutrophil-lymphocyte ratio as a predictor of severity and mortality in children and adolescents with traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Utility of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio as a predictive biomarker in pediatric traumatic brain injury.Surgical neurology international · 2024Article
- Thrombo-inflammatory prognostic score can predict the outcome of stroke: a retrospective cohort study.Frontiers in aging neuroscience · 2024Article
- Neutrophil to Lymphocyte Ratio as a Predictor of Postoperative Outcomes in Traumatic Brain Injury: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2023Review
- Screening for PTSD and TBI in Veterans using Routine Clinical Laboratory Blood Tests.Translational psychiatry · 2023Article
- Post-traumatic decompressive craniectomy: Prognostic factors and long-term follow-up.Surgical neurology international · 2023Article
- Relationship between platelet indices and red cell distribution width and short-term mortality in traumatic brain injury with 30-day mortality.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Inconsistent findings of neutrophil/lymphocyte and platelet/lymphocyte in trauma patients.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Is C-reactive protein-albumin ratio or neutrophil-lymphocyte ratio a better indicator to predict in-hospital mortality in traumatic brain injury?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Inflammatory Predictors of Prognosis in Patients with Traumatic Cerebral Haemorrhage: Retrospective Study.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNeutrophil-lymphocyte count ratio (NLCR) is a simple and low-cost marker of inflammatory response. NLCR has shown to be a sensitive marker of clinical severity in inflammatory-related tissue injury, and high value of NLCR is associated with poor outcome in traumatic brain injured (TBI) patients. The purpose of this study was to retrospectively analyze NLCR and its association with outcome in a cohort of TBI patients in relation to the type of brain injury.
methodsAdult patients admitted for isolated TBI with Glasgow Coma Score lower than eight were included in the study. NLCR was calculated as the ratio between the absolute neutrophil and lymphocyte count immediately after admission to the hospital, and for six consecutive days after admission to the intensive care unit (ICU). Brain injuries were classified according to neuroradiological findings at the admission computed tomography (CT) as DAI-patients with severe diffuse axonal injury; CE-patients with hemispheric or focal cerebral edema; ICH-patients with intracerebral hemorrhage; S-EH/SAH-patients with subdural and/or epidural hematoma/subarachnoid hemorrhage.
resultsNLCR was calculated in 144 patients. Admission NLCR was significantly higher in the non-survivors than in those who survived at 28 days (
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