Evidence map›Paper›PMID 31547379›Full record

SynthesisToxins2019

The Diversity of Cyanobacterial Toxins on Structural Characterization, Distribution and Identification: A Systematic Review.

Xingde Du, Haohao Liu, Le Yuan, Yueqin Wang, Ya Ma, Rui Wang, Xinghai Chen, Michael D Losiewicz, Hongxiang Guo, Huizhen Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Impact of high temperature and UVR exposure on the microcystin production and mcyB gene expression in the cyanobacterium Microcystis aeruginosa.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  8. Article
  9. Environmental risk factors for liver cancer.Hepatology (Baltimore, Md.) · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xingde DuCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. duxd1993@gs.zzu.edu.cn.
Haohao LiuCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. lhl2019@gs.zzu.edu.cn.
Le YuanCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. ylsir2018@gs.zzu.edu.cn.
Yueqin WangCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. wangyueqin@gs.zzu.edu.cn.
Ya MaCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. maya@gs.zzu.edu.cn.
Rui WangCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. wangrui2019@gs.zzu.edu.cn.
Xinghai ChenDepartment of Chemistry and Biochemistry, St Mary's University, San Antonio, TX 78228, USA. xchen@stmarytx.edu.
Michael D LosiewiczDepartment of Chemistry and Biochemistry, St Mary's University, San Antonio, TX 78228, USA. mlosiewicz@stmarytx.edu.
Hongxiang GuoCollege of Life Sciences, Henan Agricultural University, Zhengzhou 450002, China. guohongxiang@henau.edu.cn.
Huizhen ZhangCollege of Public Health, Zhengzhou University, Zhengzhou 450001, China. huizhenzhang@zzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread distribution of cyanobacteria in the aquatic environment is increasing the risk of water pollution caused by cyanotoxins, which poses a serious threat to human health. However, the structural characterization, distribution and identification techniques of cyanotoxins have not been comprehensively reviewed in previous studies. This paper aims to elaborate the existing information systematically on the diversity of cyanotoxins to identify valuable research avenues. According to the chemical structure, cyanotoxins are mainly classified into cyclic peptides, alkaloids, lipopeptides, nonprotein amino acids and lipoglycans. In terms of global distribution, the amount of cyanotoxins are unbalanced in different areas. The diversity of cyanotoxins is more obviously found in many developed countries than that in undeveloped countries. Moreover, the threat of cyanotoxins has promoted the development of identification and detection technology. Many emerging methods have been developed to detect cyanotoxins in the environment. This communication provides a comprehensive review of the diversity of cyanotoxins, and the detection and identification technology was discussed. This detailed information will be a valuable resource for identifying the various types of cyanotoxins which threaten the environment of different areas. The ability to accurately identify specific cyanotoxins is an obvious and essential aspect of cyanobacterial research.

Indexed as

Bacterial ToxinsMarine ToxinsMicrocystinsWater PollutantsAnimalsCyanobacteria ToxinsEnvironmental MonitoringHumansBacterial ToxinsCyanobacteria ToxinsMarine ToxinsMicrocystinsWater Pollutantscyanobacterial toxinsdistributiondiversityidentificationstructural characterization

Identifiers

PMID31547379
PMCPMC6784007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.