Evidence map›Paper›PMID 31547301›Full record

ArticlePharmaceutics2019

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable

Vanessa E Rees, Jürgen B Bulitta, Antonio Oliver, Roger L Nation, Cornelia B Landersdorfer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Vanessa E ReesCentre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville campus), Parkville, VIC 3052, Australia. roger.nation@monash.edu.ORCID 0000-0001-5372-959X
Jürgen B BulittaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA. jbulitta@cop.ufl.edu.ORCID 0000-0001-7352-3097
Antonio OliverServicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria de Palma, 07120 Palma de Mallorca, Spain. antonio.oliver@ssib.es.ORCID 0000-0001-9327-1894
Roger L NationDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville campus), Parkville, VIC 3052, Australia.
Cornelia B LandersdorferCentre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville campus), Parkville, VIC 3052, Australia. cornelia.landersdorfer@monash.edu.ORCID 0000-0003-0928-4743
Monash University · AUHospital Universitario Son Espases · ESNovo Nordisk (Denmark) · DKUniversity of Florida · US

Funding

National Health and Medical Research Council APP1101553; APP1062509; APP1084163;
6 · The paper itself

Abstract

Hypermutable

Indexed as

antibiotic combinationantibiotic resistanceantipseudomonalshypermutablemechanism-based modelling

Identifiers

PMID31547301
PMCPMC6781503
OpenAlexW2972596097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.