Trial reportNutrients2019
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly.
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- The Potential of Pectins to Modulate the Human Gut Microbiota Evaluated by In Vitro Fermentation: A Systematic Review.Nutrients · 2022Pooled it
- The Gut Microbiome, Aging, and Longevity: A Systematic Review.Nutrients · 2020Pooled it
- Trial
- Effects of Short-Term Dietary Fiber Intervention on Gut Microbiota in Young Healthy People.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Trial
- Trial
- Spatio-temporal dynamics of the human small intestinal microbiome and its response to a synbiotic.Gut microbesTrial
- Intestinal gases as markers to study the diet-gut microbiota-host metabolism axis in humans and their relationship to metabolic health.Gut microbes · 2026Review
- Safety evaluation of pectin-rich extract derived fromEFSA journal. European Food Safety Authority · 2026Article
- Effect of dietary fibre on the gastrointestinal microbiota during critical illness: A scoping review.World journal of critical care medicine · 2025Review
- Deciphering Pectin: A Comprehensive Overview of Its Origins, Processing, and Promising Utility.ACS omega · 2025Review
- Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods.Nutrients · 2024Review
- Comparative characterization of the infant gut microbiome and their maternal lineage by a multi-omics approach.Nature communications · 2024Article
- Nutritional and functional roles of β-mannanase on intestinal health and growth of newly weaned pigs fed two different types of feeds.Journal of animal science · 2024Article
- Changes of faecal bacterial communities and microbial fibrolytic activity in horses aged from 6 to 30 years old.PloS one · 2024Article
- Article
- Volatile Markers for Cancer in Exhaled Breath-Could They Be the Signature of the Gut Microbiota?Molecules (Basel, Switzerland) · 2023Article
- Agaricus subrufescens fermented rye affects the development of intestinal microbiota, local intestinal and innate immunity in suckling-to-nursery pigs.Animal microbiome · 2023Article
- Age-related effects on the modulation of gut microbiota by pectins and their derivatives: anFrontiers in microbiology · 2023Article
- Methanogen Levels Are Significantly Associated with Fecal Microbiota Composition and Alpha Diversity in Healthy Adults and Irritable Bowel Syndrome Patients.Microbiology spectrum · 2022Article
- Dietary Fiber Intake and Gut Microbiota in Human Health.Microorganisms · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
Aging is accompanied with increased frailty and comorbidities, which is potentially associated with microbiome perturbations. Dietary fibers could contribute to healthy aging by beneficially impacting gut microbiota and metabolite profiles. We aimed to compare young adults with elderly and investigate the effect of pectin supplementation on fecal microbiota composition, short chain fatty acids (SCFAs), and exhaled volatile organic compounds (VOCs) while using a randomized, double-blind, placebo-controlled parallel design. Fifty-two young adults and 48 elderly consumed 15 g/day sugar beet pectin or maltodextrin for four weeks. Fecal and exhaled breath samples were collected before and after the intervention period. Fecal samples were used for microbiota profiling by 16S rRNA gene amplicon sequencing, and for analysis of SCFAs by gas chromatography (GC). Breath was used for VOC analysis by GC-tof-MS. Young adults and elderly showed similar fecal SCFA and exhaled VOC profiles. Additionally, fecal microbiota profiles were similar, with five genera significantly different in relative abundance. Pectin supplementation did not significantly alter fecal microbiota, SCFA or exhaled VOC profiles in elderly or young adults. In conclusion, aside from some minor differences in microbial composition, healthy elderly and young adults showed comparable fecal microbiota composition and activity, which were not altered by pectin supplementation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.