Evidence map›Paper›PMID 31547289›Full record

ArticleMicroorganisms2019

Mode of Action of Dietary Dexamethasone May Not Be Dependent Upon Microbial Mechanisms in Broilers.

Audrey F Duff, Mikayla F A Baxter, B Danielle Graham, Billy M Hargis, Lisa R Bielke

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Audrey F DuffDepartment of Animal Sciences The Ohio State University, Columbus, OH 43210, USA. duff.97@osu.edu.
Mikayla F A BaxterDepartment of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA. mb022@email.uark.edu.
B Danielle GrahamDepartment of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA. bmahaffe@uark.edu.
Billy M HargisDepartment of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA. bhargis@uark.edu.
Lisa R BielkeDepartment of Animal Sciences The Ohio State University, Columbus, OH 43210, USA. bielke.1@osu.edu.
University of Arkansas at Fayetteville · USThe Ohio State University · US

Funding

USDA Hatch Project ARK02548
6 · The paper itself

Abstract

Dexamethasone (Dex), a synthetic glucocorticoid (GC), in feed has been shown to increase gut permeability via stress-mediated mechanisms, but the exact mode of action on gut barrier function is not fully understood. Stress has been reported to alter the profile and virulence of intestinal flora predisposing for opportunistic disease. This study aimed to evaluate the relationship between dietary Dex and recoverable intestinal microbial profile in broilers to better understand mode of action and refine future uses of the model. Three experiments were conducted that administered Dex-treated feed for one week in conjunction with the antibiotics BMD (bacitracin methylene disalicylate) or Baytril

Indexed as

broilersdexamethasoneenteric bacteriaintestinal healthstress

Identifiers

PMID31547289
PMCPMC6780751
OpenAlexW2972847773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.