ArticleInternational journal of environmental research and public health2019
Air Pollution and Preterm Birth: Do Air Pollution Changes over Time Influence Risk in Consecutive Pregnancies among Low-Risk Women?
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Air pollution's toll on adverse birth outcomes: key research insights from Chinese epidemiological studies.Frontiers in public health · 2025Pooled it
- Importance of STAT3 signaling in preeclampsia (Review).International journal of molecular medicine · 2025Review
- Exposure to acute ambient temperature extremes and neonatal intensive care unit admissions: A case-crossover study.The Science of the total environment · 2024Article
- Association between Liver and Kidney Function and Birth Outcomes in Pregnant Surinamese Women Exposed to Mercury and Lead in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study.Journal of xenobiotics · 2024Article
- Characterisation of personalised air pollution exposure in pregnant women participating in a birth cohort study.Paediatric and perinatal epidemiology · 2023Article
- Air Pollution and Aeroallergens as Possible Triggers in Preterm Birth Delivery.International journal of environmental research and public health · 2023Article
- Machine learning-based risk factor analysis of adverse birth outcomes in very low birth weight infants.Scientific reports · 2022Article
- Poor ovarian response is associated with air pollutants: A multicentre study in China.EBioMedicine · 2022Article
- Climate change, women's health, and the role of obstetricians and gynecologists in leadership.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Article
- World Prematurity Day: it takes an NIH village to prevent preterm birth and improve treatments for preterm infants.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Association of Preterm Birth with Depression and Particulate Matter: Machine Learning Analysis Using National Health Insurance Data.Diagnostics (Basel, Switzerland) · 2021Article
- Integrating evolution into medical education for women's health care practitioners.Evolution, medicine, and public health · 2020Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Since the 2000s, air pollution has generally continued to decrease in the U.S. To investigate preterm birth (PTB) risk associated with air pollutants in two consecutive pregnancies, we estimated exposures using modified Community Multiscale Air Quality models linked to the NICHD Consecutive Pregnancy Study. Electronic medical records for delivery admissions were available for 50,005 women with singleton births in 20 Utah-based hospitals between 2002-2010. We categorized whole pregnancy average exposures as high (>75th percentile), moderate (25-75) and low (<25). Modified Poisson regression estimated second pregnancy PTB risk associated with persistent high and moderate exposure, and increasing or decreasing exposure, compared to persistent low exposure. Analyses were adjusted for prior PTB, interpregnancy interval and demographic and clinical characteristics. Second pregnancy PTB risk was increased when exposure stayed high for sulfur dioxide (32%), ozone (17%), nitrogen oxides (24%), nitrogen dioxide (43%), carbon monoxide (31%) and for particles < 10 microns (29%) versus consistently low exposure. PTB risk tended to increase to a lesser extent for repeated PTB (19-21%) than for women without a prior PTB (22-79%) when exposure increased or stayed high. Area-level changes in air pollution exposure appear to have important consequences in consecutive pregnancies with increasing exposure associated with higher risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.