Evidence map›Paper›PMID 31547184›Full record

ArticleMolecules (Basel, Switzerland)2019

Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release.

Gregorio Carballo-Uicab, José E Linares-Trejo, Gabriela Mellado-Sánchez, Carlos A López-Morales, Marco Velasco-Velázquez, Lenin Pavón, Sergio Estrada-Parra, Sonia Mayra Pérez-Tapia, Emilio Medina-Rivero

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04379479 (Assessment of the Clinical Effect of Dialyzable Leukocyte Extracts in Individuals With Acute Respiratory Infection), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04379479 phase2unknown statusnot on this mapstarted 2020, after this paper: background citation

Assessment of the Clinical Effect of Dialyzable Leukocyte Extracts in Individuals With Acute Respiratory Infection (Suspected or Confirmed Cases of COVID-19) (FUTURE-T)

TypeinterventionalSponsorNational Polytechnic Institute, MexicoRan2020 to 2020Enrolled562ConditionsCOVID-19, SARS-CoV-2 InfectionArmsDialyzable Leukocyte Extract, Placebo oral
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Gregorio Carballo-UicabUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. gjcarballo@ipn.mx.ORCID 0000-0002-9458-0776
José E Linares-TrejoUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. jelt92@gmail.com.ORCID 0000-0001-7798-4907
Gabriela Mellado-SánchezUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. gmellados@ipn.mx.ORCID 0000-0002-8299-5958
Carlos A López-MoralesUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. carlos.lopez@udibi.com.mx.ORCID 0000-0001-8111-3127
Marco Velasco-VelázquezDepartamento de Farmacología y Unidad Periférica de Investigación en Biomedicina Traslacional (CMN 20 de noviembre, ISSSTE), Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de Mexico 04510, Mexico. marcovelasco@unam.mx.
Lenin PavónLaboratorio de Psicoinmunología, Dirección de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatría Ramón de la Fuente, Cuida de Mexico 14370, Mexico. lkuriaki@imp.edu.mx.ORCID 0000-0002-6067-6868
Sergio Estrada-ParraDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. sestradap07@hotmail.com.ORCID 0000-0002-5752-592X
Sonia Mayra Pérez-TapiaUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. sperezt@ipn.mx.ORCID 0000-0002-2818-8522
Emilio Medina-RiveroUnidad de Desarrollo e Investigación en Bioprocesos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico. emilio.medina@udibi.com.mx.ORCID 0000-0001-8862-1378
Instituto Politécnico Nacional · MXInstitute for Social Security and Services for State Workers · MXInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transferon

Indexed as

Biological AssayCell ProliferationHumansLeukocytesPeptidesPeptidesbiological potencycomplex mixture of peptidesdevelopment and validationdialyzable leukocyte extractquality specificationsTransferon®

Identifiers

PMID31547184
PMCPMC6804008
OpenAlexW2974733284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.