Evidence map›Paper›PMID 31547180›Full record

ReviewMedicina (Kaunas, Lithuania)2019

Vaginal Health in Menopausal Women.

Stefania Alvisi, Giulia Gava, Isabella Orsili, Giulia Giacomelli, Maurizio Baldassarre, Renato Seracchioli, Maria Cristina Meriggiola

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05627791 phase2 / phase3terminatednot on this mapstarted 2022, after this paper: background citation

Effects of Vaginal Oxytocin Gel on Vaginal Cytologic Parameters in Postmenopausal Woman: A Randomized Placebo-controlled Trial

TypeinterventionalSponsorDepartment of Medical Services Ministry of Public Health of ThailandRan2022 to 2023Enrolled6ConditionsVaginal Atrophy, Oxytocin Gel, Postmenopausal Women, Vaginal Maturation IndexArmsOxytocin, Placebo
NCT07153276 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Treatment of vaginal dryness in sjögren's disease with co2-laser versus topical promestriene: a prospective randomized study

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2026 to 2030Enrolled60ConditionsSjogren Syndrome, Sjogren Disease, Primary Sjogren SyndromeArmsFractional CO2 laser (vaginal), Promestriene Vaginal
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Efficacy ofNutrients · 2024
    Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefania AlvisiGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. stefania.alvisi@gmail.com.
Giulia GavaGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. gava.giulia@hotmail.it.
Isabella OrsiliGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. isabella.orsili@libero.it.
Giulia GiacomelliGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. giuliagiacomelli90@gmail.com.
Maurizio BaldassarreDepartment of Surgical and Medical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. maurizio.baldassarre@unibo.it.
Renato SeracchioliGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. renato.seracchioli@aosp.bo.it.
Maria Cristina MeriggiolaGynecology and Physiopathology of Human Reproduction Unit, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy. cristina.meriggiola@unibo.it.ORCID 0000-0003-0061-9834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review is to provide an overview of genitourinary health in peri- and postmenopause, particularly of vulvovaginal atrophy (VVA), which is part of genitourinary syndrome (GSM). This condition has a high prevalence among post-menopausal women and negatively affects a woman's quality of life. Epidemiology, signs, symptoms, diagnostic criteria of VVA and target treatments for restoring vaginal health are discussed in light of the most recent literature. Issues related to this condition in menopausal women are under-diagnosed, lack objective diagnostic criteria, and consequently under-treated. Over the years, many treatments have been developed but their long-term effectiveness and safety have yet to be clearly defined. Patients are often dissatisfied and stop treatment, suggesting the need for a more personalized and tailored approach to achieve better compliance and thereby effectiveness. The aim of this paper is to provide an overview of the most recent literature on VVA in order to help the gynecologist in the management of this condition.

Indexed as

Hormone Replacement TherapyAdministration, IntravaginalAtrophyEmollientsFemaleHumansLaser TherapyLubricantsPerimenopausePostmenopauseVaginaVaginal DiseasesEmollientsLubricantsgenitourinary syndromemenopausal womenvaginal healthvulvovaginal atrophy

Identifiers

PMID31547180
PMCPMC6843679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.